Skip to main content
Accessibility|Contact|Privacy|Terms of Service

Schizophrenia and Psychotic Syndromes

  • Published: 2010-08-29 : Author: European College of Neuropsychopharmacology
  • Synopsis: Schizophrenia and related psychotic disorders are a chronic and often disabling condition.

Main Document

Press conference on the occasion of the 23rd ECNP Congress, Aug. 29, 2010, Amsterdam.

Schizophrenia and related psychotic disorders are a chronic and often disabling condition. Despite modern treatment techniques they still present an enormous burden to the patients and their relatives and take a serious toll in terms of human suffering and societal expenditure.

The diagnosis of schizophrenia is associated with demonstrable alterations in brain structure and changes in neurotransmission, with increased dopamine action being directly related to typical positive symptoms such as hallucinations and delusions. Negative symptoms include restricted range and intensity of emotional expression, reduced thought and speech, and social withdrawal. In general, schizophrenia presents a bewildering complexity of symptoms in multiple domains in great heterogeneity across individuals and also variability within individuals over time.

Psychotic symptoms typically emerge in adolescence and early adulthood, although late-onset cases (in patients aged over 40 years) have been identified. Around 2-3% of adolescents and young adults will develop a psychotic disorder, and many of them will experience successive episodes throughout their lives, with progressive deterioration that leaves them persistently symptomatic and functionally impaired. In most industrialized countries 1-2 years pass before adequate treatment is initiated. Research indicates that delayed access to health services and treatment is associated with slower or less complete recovery and increased risk of relapse in the subsequent 2 years (Falkai et al., 2005).

Even today psychotic disorders remain highly stigmatized, and despite the young age of the patients and the long-term service dependence often are not prioritized in the agenda of public health.

Reference - Falkai P, Wobrock T, Lieberman J, et al. World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Schizophrenia. The World Journal of Biological Psychiatry 2005;6:132-191

Similar Topics

1 : Link Between Excessive Screen Time and Teen Suicide Risk : Florida State University.
2 : Facial Recognition Findings May Help Develop Conduct Disorder Treatments : University of Bath.
3 : Social Isolation and Loneliness Greater Threat to Public Health Than Obesity : American Psychological Association.
4 : Control Your Emotions by Talking to Yourself in the 3rd Person : Michigan State University.
5 : New Diagnostic Model For Psychiatric Disorders Proposed : University of Notre Dame.
From our Psychological Disorders section - Full List (78 Items)


Submit disability news, coming events, as well as assistive technology product news and reviews.


Loan Information for low income singles, families, seniors and disabled. Includes home, vehicle and personal loans.


Famous People with Disabilities - Well known people with disabilities and conditions who contributed to society.


List of awareness ribbon colors and their meaning. Also see our calendar of awareness dates.


Blood Pressure Chart - What should your blood pressure be, and information on blood group types/compatibility.





1 : Bias Keeps Women with Higher Body Weight Away From the Doctor
2 : Smart Hoteliers are Building a Healthier Future
3 : Teaching Baby Sign Language - Nita, Show Us More
4 : MitoQ Novel Antioxidant Makes Old Arteries Seem Young Again
5 : Telemedicine Helps Overcome Healthcare Gender Based Barriers
6 : Screen Reader Plus Keyboard Helps Blind, Low-Vision Users Browse Modern Webpages
7 : Our Digital Remains Should be Treated with Same Care and Respect as Physical Remains
8 : Tungsten: Concern Over Possible Health Risk by Human Exposure to Tungsten


Disclaimer: This site does not employ and is not overseen by medical professionals. Content on Disabled World is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. See our Terms of Service for more information.

Reporting Errors: Disabled World is an independent website, your assistance in reporting outdated or inaccurate information is appreciated. If you find an error please let us know.

© 2004 - 2018 Disabled World™