MENUHomeNewsTopics A - Z
Accessibility|Contact|Privacy|Terms|Cookies

Folic Acid May Help Heal Spinal Cord and Brain Injuries


  • Published: 2010-04-26 (Revised/Updated 2012-04-22) : Author: Journal of Clinical Investigation
  • Synopsis: Understanding how folic acid might help heal brain and spinal cord injuries.

Understanding how folic acid might help heal brain and spinal cord injuries.

Folic Acid - Also known as folate or folacin when it naturally occurs in foods, is a B vitamin that is essential for the healthy development of a baby's spine, brain and skull during the early weeks of pregnancy. All people need folic acid. But folic acid is very important for women who are able to get pregnant. Folic acid is found naturally in some foods, including leafy vegetables, citrus fruits, beans (legumes), and whole grains. Enriched breads, cereals and other grain products also contain folic acid. If you don't get enough folic acid from the foods you eat, you can also take it as a dietary supplement.

Babies born to women who do not consume enough folic acid (sometimes referred to as folate or vitamin B9) are at high risk of developing neural tube defects (i.e., defects in the development of the spinal cord or brain).

This is the reason underlying the recommendation that women who are pregnant take a folic acid supplement.

A team of researchers, led by Bermans Iskandar, at the University of Wisconsin, Madison, has now generated data in rodents suggesting that folic acid might also help promote healing in injured brain and spinal cord. Specifically, the team was able to uncover a molecular pathway by which folate can promote nerve cell regeneration following injury in rodents.

In an accompanying commentary, Matthias Endres and Golo Kronenberg, at Charite - Universitatsmedizin Berlin, Germany, discuss how these data, together with the safety and simplicity of folate supplementation, provide a rationale for testing whether folate supplementation is beneficial for patients with spinal cord and brain trauma.

TITLE: Folate regulation of axonal regeneration in the rodent central nervous system through DNA methylation

AUTHOR CONTACT:
Bermans J. Iskandar
University of Wisconsin, Madison, Wisconsin, USA.
Phone: 608.263.9651; Fax: 608.263.1728; E-mail: iskandar@neurosurg.wisc.edu.

View this article at: www.jci.org/articles/view/40000key=7699cee3397c28e321ac

ACCOMPANYING COMMENTARY
TITLE: Neuronal injury: folate to the rescue

AUTHOR CONTACT:
Matthias Endres
Charite - Universitatsmedizin Berlin, Berlin, Germany.
Phone: 49.30.450.560.102; Fax: 49.30.450.560.932; E-mail: matthias.endres@charite.de.

View this article at: www.jci.org/articles/view/40764key=TpndN64MezO2HHZ2NCmW

Submit disability news, coming events, as well as assistive technology product news and reviews.


Loan Information for low income singles, families, seniors and disabled. Includes home, vehicle and personal loans.


Famous People with Disabilities - Well known people with disabilities and conditions who contributed to society.


List of awareness ribbon colors and their meaning. Also see our calendar of awareness dates.


Blood Pressure Chart - What should your blood pressure be, and information on blood group types/compatibility.






Disclaimer: This site does not employ and is not overseen by medical professionals. Content on Disabled World is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. See our Terms of Service for more information.

Reporting Errors: Disabled World is an independent website, your assistance in reporting outdated or inaccurate information is appreciated. If you find an error please let us know.

© 2004 - 2018 Disabled World™