Skip to main content
Accessibility|Contact|Privacy|Terms|Cookies

Retinopathy of Prematurity - Early Treatment Benefits Some Children

  • Published: 2010-04-13 : Author: JAMA and Archives Journals
  • Synopsis: Early treatment associated with benefits for some children with Retinopathy of prematurity.

Main Document

Early treatment associated with benefits for some children with Retinopathy of prematurity.

Certain children with the visual condition known as Retinopathy of prematurity appear to see better at age 6 if they received treatment early, whereas others benefit more from observation than early treatment, according to a report posted online today that will appear in the June print issue of Archives of Ophthalmology , one of the JAMA/Archives journals.

Retinopathy of prematurity occurs in babies born early; abnormal blood vessels and scar tissue grow over the retina, decreasing vision. A previous study on Retinopathy of prematurity helped researchers identify two types of the condition, Type 1 and Type 2, based on various clinical characteristics, according to background information in the article. Differences between the two include stage of disease, area of the retina affected and the presence or absence of plus disease (severe growth of additional blood vessels in the back of the eye).

In the previous study of 401 infants whose eyes were randomly assigned to early treatment or conventional management, early treatment appeared to show a benefit at 9 months. The Early Treatment for Retinopathy of Prematurity Cooperative Group followed the same group of children through 6 years of age (370 had survived).

Overall, early treatment was not associated with improved vision at 6 years. However, eyes of children with Type 1 Retinopathy of prematurity appeared to have improved vision at age 6 if they were treated early (25.1 percent vs. 32.8 percent had an unfavorable outcome). There did not appear to be a benefit of early treatment for eyes of children with Type 2 Retinopathy at age 6 (23.6 percent vs. 19.4 percent unfavorable outcomes).

In the original nine-month study, "the analysis identified eyes with characteristics indicating a benefit for early treatment (Type 1) and eyes that could be observed (Type 2), with treatment offered if the disease progressed to Type 1," the authors write. "These divisions into Type 1 and Type 2 eyes were not preplanned as part of the original design in 1999 but came about in 2003 as a result of analysis of initial study outcome data. There was an obligation to follow these eyes according to this subdivision once the types had been developed and published."

The results demonstrate that the benefit of treatment for children with Type 1 disease lasts as long as six years, they note. "Visual acuity is improved with early treatment, but nevertheless, 65.4 percent of eyes receiving early treatment develop visual acuity worse than 20/40. Whether this result is due to retinal, cortical or both factors remains to be determined, but clearly prevention of Retinopathy of prematurity now assumes an even higher priority since early treatment is beneficial for some eyes but often does not result in normal development of visual acuity."

Discussion

• Have your say! Add your comment or discuss this article on our FaceBook Page.

Similar Topics

1 : Unexpected Finding May Deter Diabetic Retinopathy Eye Disease : Michigan State University.
2 : International Clinical Trial Study of AMD Progression : NIH - National Eye Institute (NEI).
3 : People Who Experience Dry Eye Soon to Have Drug-Free Solution : American Academy of Ophthalmology.
4 : Do Blind People Express Emotions the Same Way as Sighted People : Universite de Geneve.
5 : Visually-Impaired Children Experience Egg Hunt with Eggs That Beep : Bureau of Alcohol, Tobacco, Firearms and Explosives (ATF).
From our Vision Disability section - Full List (73 Items)


Submit disability news, coming events, as well as assistive technology product news and reviews.


Loan Information for low income singles, families, seniors and disabled. Includes home, vehicle and personal loans.


Famous People with Disabilities - Well known people with disabilities and conditions who contributed to society.


List of awareness ribbon colors and their meaning. Also see our calendar of awareness dates.


Blood Pressure Chart - What should your blood pressure be, and information on blood group types/compatibility.





1 : 20 New Episodes of Letters to Lynette with Dr. Lynette Louise to Air on The Autism Channel in 2018
2 : Turnstone Center Designated as Official Paralympic Training Site by US Olympic Committee
3 : Help Your Child in School by Adding Language to The Math
4 : 50% of Retirees Saw Little or No COLA Increase in Net 2018 Social Security Benefits
5 : Turnstone Endeavor Games Concludes with National Records Broken
6 : Spinning in Circles and Learning From Myself by Tsara Shelton
7 : St. Louis HELP Medical Equipment Donation Drive Generates Record-Breaking Results
8 : People Who Snore Suffer from Palate Nerve and Muscle Damage


Disclaimer: This site does not employ and is not overseen by medical professionals. Content on Disabled World is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. See our Terms of Service for more information.

Reporting Errors: Disabled World is an independent website, your assistance in reporting outdated or inaccurate information is appreciated. If you find an error please let us know.

© 2004 - 2018 Disabled World™