Teen BMI Weight Linked to Heart Failure Risk in Early Middle Age
Author: European Society of Cardiology(i) : Contact: escardio.org
Published: 2016-06-17 : (Rev. 2020-10-10)
Synopsis and Key Points:
Findings show importance of body weight in adolescence and suggest more emphasis be placed on maintenance of a healthy body weight from early age as preventive measure.
Given the global trend for growing numbers of teenagers to be overweight and obese, our findings suggest that heart failure, which in this study occurred at the relatively early average age of about 47 may well become a major threat to health worldwide.
Current prevention guidelines are meant to guide doctors treating patients with factors that may put them at increased risk of heart and blood vessel problems within the next decade or so.
Research that followed more than 1.6 million Swedish men from adolescence onwards between 1968 and 2005 has shown that those who were overweight as teenagers were more likely to develop heart failure in early middle age.
What Exactly is Body Mass Index (BMI)?
The body mass index (BMI), or Quetelet index, is defined as a value derived from the mass (weight) and height of an individual. The BMI is defined as the body mass divided by the square of the body height, and is universally expressed in units of kg/m2, resulting from weight in kilograms and height in meters. If pounds and inches are used, a conversion factor of 703 (kg/m2)/(lb/in2) must be applied. When the term BMI is used informally, the units are usually omitted. A high BMI can be an indicator of high body fatness. BMI can be used as a screening tool but is not diagnostic of the body fatness or health of an individual.
Surprisingly, the increased risk of heart failure was found in men who were within the normal body weight range (a body mass index of 18.5 to 25) in adolescence, with an increased risk starting in those with a BMI of 20 and rising steeply to a nearly ten-fold increased risk in those who were very obese, with a BMI of 35 or over.
The study, which is published in the European Heart Journal , found that in men with a BMI of 20 and over, the risk of heart failure increased by 16% with every BMI unit, after adjustments for factors that could affect the findings, such as age, year of enlistment into the Swedish armed forces, other diseases, parental education, blood pressure, IQ, muscle strength and fitness.
Annika Rosengren, Professor of Medicine at the Sahlgrenska Academy (Gothenburg, Sweden), who led the research, said:
"Although most studies define a normal weight as having a BMI between 18.5 and 25, this is probably not an appropriate definition in the young, most of whom are naturally thin. This may be why we see an increase in the risk of heart failure starting at a fairly low BMI level. However, it was surprising to see the very steep increase in risk with increasing body weight above a BMI of 20."
"Given the global trend for growing numbers of teenagers to be overweight and obese, our findings suggest that heart failure, which in this study occurred at the relatively early average age of about 47 may well become a major threat to health worldwide. This serves to underline the urgent need for action worldwide to curb the obesity epidemic. Action needs to be taken by governments as well as by individuals, for instance by creating an environment that does not promote overweight and obesity, and that encourages people not to be sedentary and not to eat more than they need. This is more important than hassling people into dieting whatever shape they are. Once established, overweight and obesity is much harder to tackle."
Until recently, Swedish law required all 18-year-old Swedish men to enlist in the armed forces, and between 1968 and 2005 a total of 1,810,348 men enlisted and underwent standardised physical and cognitive examinations. For this study Professor Rosengren and her colleagues analysed data on 1,610,437 men from the Swedish Conscript registry. They followed the men from the time they enlisted at 18, for between five to 42 years (an average follow-up time of 23 years). During that time, 5,492 men were admitted to hospital for heart failure, with an average age at diagnosis of nearly 47.
Compared with men who had a BMI of between 18.5 and 20 at the time of conscription:
- Men with a BMI of 20 to 22.5 had a 22% increased risk of heart failure, after adjusting for factors that could affect the results.
- The risk nearly doubled for those with a BMI between 22.5 and 25, and more than tripled for those with a BMI between 25 and 27.5.
- The risk increased more than six-fold for those classified as obese with a BMI between 30-35, and was nearly 10-fold for the very obese with a BMI of 35 or more.
The researchers say their findings suggest that preventive action needs to be taken earlier in life.
Prof Rosengren said:
"Current prevention guidelines are meant to guide doctors treating patients with factors that may put them at increased risk of heart and blood vessel problems within the next decade or so. The overwhelming majority of young people have an extremely low risk of any such problems and so are not in need of preventive measures on an individual basis, except for firm anti-smoking advice. However, our findings show the importance of body weight in adolescence and suggest that more emphasis should be placed on the maintenance of a healthy body weight from an early age as a preventive measure."
The researchers point out that limitations to the study include the fact that their findings are only applicable to men and that, overall, women have a lower risk of heart failure than men; nor did they have any information on weight gain after the men were conscripted at 18, so that a slightly greater weight at 18, might be an indicator of an increased risk of subsequently becoming overweight or obese, which in itself, would be a risk factor for heart failure. However, the strength of the study is its large size, with over 1.6 million participants.
 "Body weight in adolescence and long-term risk of early heart failure in adulthood among men in Sweden", by Annika Rosengren et al. European Heart Journal. doi:10.1093/eurheartj/ehw125
(i)Source/Reference: European Society of Cardiology. Disabled World makes no warranties or representations in connection therewith. Content may have been edited for style, clarity or length.
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