Rheumatoid Arthritis Patients and Doctors Differ on Disease Severity
Synopsis: RA patients and doctors differ on severity assessment as depressed patients show highest level of discord in evaluating their disease.1
Main DigestStudy shows RA patients and doctors differ on disease severity assessment - Depressed patients showed highest level of discord in evaluating their disease.
A novel study by researchers at the University of California, San Francisco found that nearly one-third of Rheumatoid Arthritis (RA) patients differed from their physicians in assessment of their disease severity. The disagreement between patient and doctor evaluation of RA activity was most prevalent in patients with depressive symptoms, and those who had poor overall function. Details of the study, the first to examine discordance in an ethnically diverse population, are published in the June issue of Arthritis Care & Research, a journal of the American College of Rheumatology.
According to a 2003 report from the World Health Organization (WHO) the prevalence of RA, an autoimmune disease characterized by painful swelling of the lining of the joints, varies between 0.3% and 1%. In the U.S. experts estimate roughly 1 to 2 million Americans have RA which affects twice as many women than men.
While clinicians who treat patients with diseases such as diabetes or hypertension have a gold standard diagnostic (glucose blood test or blood pressure) to accurately measure disease activity, rheumatologists rely on subjective (patient self-report) and objective measures (physician-assessed joint counts, acute-phase reactants) to determine RA disease activity. An accurate assessment of RA activity is essential in determining the severity of disease, monitoring response to treatment, and is particularly important with the advent of effective, but potentially toxic therapies. Clear patient-physician communication around symptom reporting and assessment of disease activity is central to the management of RA. While prior studies have documented discordance in RA, none have examined the possible association of patient language or mood with discordance, both of which pose barriers to communication.
"The need for patient-provider agreement in disease activity assessment is critical to the safe and effective management of RA," said Jennifer Barton, M.D., from the Department of Medicine, Rheumatology Division, at the University of California, San Francisco, and lead author of the study. The research team recruited 223 participants from the UCSF Rheumatoid Arthritis Cohort, a dual-site observational study, who were consecutively enrolled from the Rheumatoid Arthritis Clinic at San Francisco General Hospital and the UCSF Arthritis Center. Participants had a mean age of 53 (Plus/Minus14 years) and 88% were women. The ethnic breakdown of the study sample was 45% Latino, 27% Asian/Pacific Islander, 16% Caucasian, 10% African American, 2% American Indian or other.
Researchers gathered clinical data on each subject including rheumatoid factor, sedimentation rate, and tender and swollen joint counts, as well as the patient global assessment of disease severity as measured on a visual analog scale at each visit. Functional status was measured using the Health Assessment Questionnaire (HAQ). The 9-item Patient Health Questionnaire was used to measure depressive symptoms.
"We found clinically meaningful differences between patient and physician assessments of RA disease severity in 36% of cases," confirmed Dr. Barton. "In an overwhelming majority (85%) of these discordant pairs, the physicians' assessments underscored the patients' assessments." Researchers found that the mean VAS score for global disease severity was 46 Plus/Minus 26 mm for patients and 31 Plus/Minus 21 mm for physicians.
The research team also found that depressive symptoms were common with 30% of participants exhibiting major depression, and these patients had greater odds of discordance with their physicians than those who were not depressed. Researchers noted a lower level of patient-doctor discordance in those patients who had a higher swollen joint count, but discordance persisted in those patients with poorer functional status (HAQ score). "Reducing patient-doctor discordance is an important goal that can improve patient outcomes," concluded Dr. Barton. "Further investigation of the relationships between mood, disease activity, and discordance may help guide interventions that improve RA patient care."
Article: "Patient-Physician Discordance in Assessments of Global Disease Severity in Rheumatoid Arthritis." Jennifer L. Barton, John Imboden, Jonathan Graf, David Glidden, Edward H. Yelin, and Dean Schillinger. Arthritis Care and Research; Published Online: February 12, 2010 (DOI:10.1002/acr.20132); Print Issue Date: June 2010. www3.interscience.wiley.com/journal/123283255/abstract
This study is published in Arthritis Care & Research. Media wishing to receive a PDF of this article may contact email@example.com
Arthritis Care & Research is an official journal of the American College of Rheumatology, and the Association of Rheumatology Health Professionals, a division of the College. Arthritis Care & Research is a peer-reviewed research publication that publishes both original research and review articles that promote excellence in the clinical practice of rheumatology. Relevant to the care of individuals with arthritis and related disorders, major topics are evidence-based practice studies, clinical problems, practice guidelines, health care economics, health care policy, educational, social, and public health issues, and future trends in rheumatology practice. For more information on Arthritis Care & Research, please visit www3.interscience.wiley.com/journal/123227259/grouphome/home.html.
Wiley-Blackwell is the international scientific, technical, medical, and scholarly publishing business of John Wiley & Sons, Inc., with strengths in every major academic and professional field and partnerships with many of the world's leading societies. Wiley-Blackwell publishes nearly 1,500 peer-reviewed journals and 1,500+ new books annually in print and online, as well as databases, major reference works and laboratory protocols. For more information, please visit www.wileyblackwell.com or www.interscience.wiley.com.
Related Rheumatoid Arthritis Documents
Full List of Rheumatoid Arthritis Publications Full List of Disabled World News Updates
Recent Disability News and Updates
Full List of Disabled World News Updates
Disclaimer: Disabled World is strictly a news and information website provided for general informational purpose only and does not constitute medical advice. Materials presented are in no way meant to be a substitute for professional medical care by a qualified practitioner, nor should they be construed as such. Please report outdated or inaccurate information to us.
Disclosure: Disabled World is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com. Any 3rd party offering or advertising on disabled-world.com does not constitute endorsement by Disabled World. View our Advertising Policy for further information.