Adrenal Cancer: Symptoms, Stages, Information

Introduction

Alternate names: Adrenal Carcinoma, Adrenocortical Carcinoma, Adrenocortical Cancer, Cancer of the Adrenal Cortex, Carcinoma of the Adrenal Cortex. Adrenal Cancer forms in the outer tissue layer of the adrenal gland. Adrenocortical Carcinoma is also called Cancer of the Adrenal Cortex.

The U.S. Social Security Administration (SSA) has included Adrenal Cancer as a Compassionate Allowance to expedite a disability claim.

Main Item

A tumor of the adrenal cortex may be functioning (producing excess hormones) or non-functioning (not producing hormones). Individuals with the hereditary diseases LiFraumeni Syndrome, Beckwith-Wiedemann Syndrome, and Carney Complex are at risk for Adrenal Cancer.

Symptoms of Adrenocortical Carcinoma Include:

• A lump in the abdomen
• Pain the abdomen or back
• A feeling of fullness in the abdomen

The following may be used to diagnose the disease:

• X-rays
• MRI
• CT scan
• Laboratory tests including blood and urine analysis

Having certain genetic conditions increases the risk of adrenocortical carcinoma.

Stages of Adrenocortical Carcinoma

After diagnosing adrenocortical carcinoma, tests determine if cancer cells have spread within the adrenal gland or to other body parts. The following stages are used for adrenocortical carcinoma:

• Stage I - In stage I, the tumor is 5 centimeters or smaller and is found in the adrenal gland only.
• Stage II - In stage II, the tumor is larger than 5 centimeters and is only found in the adrenal gland.
• Stage III - In stage III, the tumor is any size and has spread to nearby lymph nodes; or nearby tissues or organs (kidney, diaphragm, pancreas, spleen, or liver) or large blood vessels (renal vein or vena cava) and may have spread to nearby lymph nodes.
• Stage IV - In stage IV, the tumor is any size, may have spread to nearby lymph nodes, and has spread to other parts of the body, such as the lung, bone, or peritoneum.

Treatment may include surgery, radiation therapy, and/or chemotherapy. Treatment for inoperable or unresectable tumors can be utilized for palliation, but the prognosis is poor.

Adrenocortical carcinoma can recur (come back) after it has been treated. The 5-year survival rate for inoperable or unresectable tumors is less than 10%.