Anaplastic Adrenal Cancer
Published: 2009-04-01 - Updated: 2023-01-28
Author: Disabled World | Contact: Disabled World (Disabled-World.com)
Peer-Reviewed Publication: N/A
Additional References: Cancer and Tumors Publications
Synopsis: Anaplastic Adrenal Cancer is a sub-type of adrenal cancer which shows virtually no cellular differentiation. CT and MRI imaging are used to diagnose adrenal lesions, but a biopsy is required for a definite diagnosis. The median survival for anaplastic adrenal cancer is five months compared to a median survival of 40 months for differentiated adrenal cancers.
Adrenocortical cancers (ACs) are uncommon malignancies that can have protean clinical manifestations. Adrenocortical masses are common; autopsy studies show that approximately 5-15% of the general adult population may have adrenal incidentalomas. Anaplastic Adrenal Cancer is a sub-type of adrenal cancer that shows virtually no cellular differentiation. It is not associated with the overproduction of hormones as in other adrenal carcinomas. Abdominal pain is a presenting symptom.
The U.S. Social Security Administration (SSA) has included Anaplastic Adrenal Cancer - with distant metastases or inoperable, resectable or recurrent as a Compassionate Allowance, which expedites certain disability conditions claims.
Adrenocortical Cancer Alternate Names:
- Adrenal Carcinoma
- Anaplastic Adrenal Cancer
- Adrenocortical carcinoma
- Adrenal cortical carcinoma (ACC)
- Adrenal cortex cancer
Regardless of size, approximately 1 per 1500 adrenal tumors are malignant. The evaluation of these incidentalomas, therefore, focuses on
- (1) identifying functional masses and treating them appropriately (including surgical removal).
- (2) identifying adrenal carcinomas early, with the intent of attempting complete surgical extirpation.
- (3) reassuring the patients who do not fit either of these classes and arranging for their subsequent follow-up.
CT and MRI imaging are used in the diagnosis of adrenal lesions, but a biopsy is required for a definite diagnosis.
Radical surgical excision is the treatment for individuals with localized malignancies and remains the only method by which long-term disease-free survival may be achieved.
Median survival for anaplastic adrenal cancer is five months compared to a median survival of 40 months for differentiated adrenal cancers.
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