Anaplastic Adrenal Cancer

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Adrenocortical cancers (ACs) are uncommon malignancies that can have protean clinical manifestations. Adrenocortical masses are common; autopsy studies show that approximately 5-15% of the general adult population may have adrenal incidentalomas. Anaplastic Adrenal Cancer is a sub-type of adrenal cancer that shows virtually no cellular differentiation. It is not associated with the overproduction of hormones as in other adrenal carcinomas. Abdominal pain is a presenting symptom.

The U.S. Social Security Administration (SSA) has included Anaplastic Adrenal Cancer - with distant metastases or inoperable, resectable or recurrent as a Compassionate Allowance to expedite a disability claim.

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Adrenocortical Cancer Alternate Names:

• Adrenal Carcinoma
• Anaplastic Adrenal Cancer
• Adrenocortical carcinoma
• Adrenal cortical carcinoma (ACC)
• Adrenal cortex cancer

Regardless of size, approximately 1 per 1500 adrenal tumors are malignant. The evaluation of these incidentalomas, therefore, focuses on

• (1) identifying functional masses and treating them appropriately (including surgical removal).
• (2) identifying adrenal carcinomas early, with the intent of attempting complete surgical extirpation.
• (3) reassuring the patients who do not fit either of these classes and arranging for their subsequent follow-up.

CT and MRI imaging are used in the diagnosis of adrenal lesions, but a biopsy is required for a definite diagnosis.

Radical surgical excision is the treatment for individuals with localized malignancies and remains the only method by which long-term disease-free survival may be achieved.

Median survival for anaplastic adrenal cancer is five months compared to a median survival of 40 months for differentiated adrenal cancers.

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Cite This Page (APA): Disabled World. (2009, April 1). Anaplastic Adrenal Cancer. Disabled World. Retrieved September 23, 2023 from www.disabled-world.com/health/cancer/anaplastic-adrenal-cancer.php

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