Skip to main content

Osteosarcoma: Common Form of Bone Cancer

  • Synopsis: Published: 2009-04-01 (Revised/Updated 2015-06-27) - Osteosarcoma is the most common type of bone cancer affecting the large bones of the arm or leg and occurs most often in younger individuals - Disabled World (Disabled World).

Main Document

Quote: "Many patients first complain of pain that may be worse at night, and may have been occurring for some time. If the tumor is large, it can appear as a swelling."

Osteosarcoma is the most common type of bone cancer. It usually affects the large bones of the arm or leg and occurs most often in younger individuals. It affects more males than females. In children and adolescents, tumors appear most often in the bones around the knee.

Osteogenic Sarcoma is the 6th leading cancer in children under age 15. Osteogenic Sarcoma affects 400 children under age 20 and 500 adults (most between the ages of 15-30) every year in the USA. Approximately 1/3 of the 900 will die each year, or about 300 a year.

A second peak in incidence occurs in the elderly, usually associated with an underlying bone pathology such as Paget's disease, Medullary infarct, or prior irradiation. Although about 90% of patients are able to have limb-salvage surgery, complications, such as infection, prosthetic loosening and non-union, or local tumor recurrence may cause the need for further surgery or amputation.

Alternate Names:

Osteosarcoma, Bone Carcinoma, Ewing's Sarcoma, Chondrosarcoma, Osteogenic Sarcoma, Multifocal Osteosarcoma, Metastatic Osteosarcoma

Symptoms of Bone Cancer:

Many patients first complain of pain that may be worse at night, and may have been occurring for some time. If the tumor is large, it can appear as a swelling. The affected bone is not as strong as normal bones and may fracture with minor trauma (a pathological fracture).

The following may be used to diagnose the disease:

biopsy, x-rays, and/or blood tests.

Most Osteosarcoma arise from random and unpredictable errors in the DNA of growing bone cells during times of intense bone growth. There currently isn't an effective way to prevent this type of cancer. But with the proper diagnosis and treatment, most kids with osteosarcoma do recover.

If the tumor is inoperable or unresectable, radiation therapy and chemotherapy may be utilized, but the prognosis remains poor.

Inoperable or unresectable osteosarcoma will likely progress locally and may spread to the lungs. Radiation is effective as a palliative measure.



Information from our Cancer: Types, Symptoms and Treatments section - (Full List).

E-Newsletter

Loan Information for low income singles, families, seniors and disabled. Includes home, vehicle and personal loans.


Famous People with Disabilities - Well known people with disabilities and conditions who contributed to society.


List of awareness ribbon colors and their meaning. Also see our calendar of awareness dates.


Blood Pressure Chart - What should your blood pressure be. Also see information on blood group types and compatibility.


  1. Majority in Favor of Spinal Muscular Atrophy (SMA) Screening
  2. When the Spinal Cord Takes Charge of Information Related to Movement
  3. Sign Language Comparative List of Astronomical Words
  4. Israeli President Honors Special Education Teachers




Citation



Errors: Disabled World is an independent website, your assistance in reporting outdated or inaccurate information is appreciated. If you find an error please let us know.

Disclaimer: Content on Disabled World is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. See our Terms of Service for more information.