Skip to main content

Improved Prognosis for Esophageal Cancer

  • Synopsis: Published: 2011-05-25 - The main cause of esophageal cancer is reflux of gastric acid from the stomach with heartburn the main symptom. For further information pertaining to this article contact: Deutsches Aerzteblatt International.
  • Jump to:

Main Document

The main cause of this cancer is reflux of gastric acid from the stomach, with heartburn as the main symptom.

In recent years, the number of cases of adenocarcinoma of the esophagus (or gullet) has been on the rise. At the same time, however, new ways of treatment are improving the outlook for patients.

In the current issue of Deutsches Arzteblatt International (Dtsch Artzebl Int 2011; 108[18]: 313), Angelika Behrens and her working group report on innovations in diagnosis and treatment.

The main cause of this cancer is reflux of gastric acid from the stomach, with heartburn as the main symptom. Other risk factors are being male, being overweight, and having relatives with this disease.

Today we are able to discover and treat adenocarcinoma (Barrett's carcinoma) at an early stage. This has chiefly been made possible by the introduction of high-definition video-endoscopy and endosonography (endoscopic ultrasound).

Locally restricted tumors can be resected endoscopically.

For locally advanced Barrett's carcinoma, the standard treatment is surgery combined with chemotherapy.

For esophageal cancer that has already metastasized, there are new approaches to therapy based at the molecular level. So-called molecular targeting uses antibodies or small molecules to alter signal transduction directly inside the tumor cell and thus inhibit growth.

The authors also report on their experience of treating over 1000 patients with this cancer.





Information from our Cancer: Types, Symptoms and Treatments section - (Full List).


     What will I receive?

Loan Information for low income singles, families, seniors and disabled. Includes home, vehicle and personal loans.


Famous People with Disabilities - Well known people with disabilities and conditions who contributed to society.


List of awareness ribbon colors and their meaning. Also see our calendar of awareness dates.


Blood Pressure Chart - What should your blood pressure be. Also see information on blood group types and compatibility.


  1. Ghana Seeks to End Chaining of 'Mad' People
  2. #Bonespiration: Hashtag Used to Promote Skeletal Images on Social Media
  3. Special Unit: Action Comedy Film Led By Cast of Actors with Disabilities
  4. Can Adults Develop ADHD?




Citation