Predicting Spread of Liver Cancer

Author: Journal of Clinical Investigation
Published: 2011/02/02
Contents: Summary - Main - Related Publications

Synopsis: Potential biomarker for predicting future metastasis in patients with the most common form of liver cancer.

Main Digest

Patients with cancer usually do not die as a result of their originally diagnosed tumor. However, many do so as a result of metastatic disease - tumors that arise at distant sites after spreading from the original tumor.

Identifying biomarkers of tumor metastasis would therefore be of immense clinical benefit.

In this context, a team of researchers - led by Peng Loh, at the National Institutes of Health, Bethesda; and Ronnie Poon, at the The University of Hong Kong, China - has now identified a potential biomarker for predicting future metastasis in patients with the most common form of liver cancer (hepatocellular carcinoma [HCC]).

Specifically, the team found that quantification of the mRNA template for a truncated version of the protein carboxypeptidase E (CPE) in HCC patient samples predicted intrahepatic metastasis with high sensitivity and specificity.

They therefore suggest that this truncated protein could be a powerful biomarker for predicting future metastasis in patients with HCC and thereby be of use to clinicians, helping guide therapeutic decisions.

📢 Discover Related Topics


👍 Share This Information To:
𝕏.com Facebook Reddit

Page Information, Citing and Disclaimer

Disabled World is an independent disability community founded in 2004 to provide disability news and information to people with disabilities, seniors, their family and/or carers. You can connect with us on social media such as X.com and our Facebook page.

Cite This Page (APA): Journal of Clinical Investigation. (2011, February 2). Predicting Spread of Liver Cancer. Disabled World. Retrieved April 16, 2024 from www.disabled-world.com/health/cancer/liver/spread.php

Permalink: <a href="https://www.disabled-world.com/health/cancer/liver/spread.php">Predicting Spread of Liver Cancer</a>: Potential biomarker for predicting future metastasis in patients with the most common form of liver cancer.

Disabled World provides general information only. Materials presented are never meant to substitute for qualified professional medical care. Any 3rd party offering or advertising does not constitute an endorsement.