Earlier Detection of Melanoma Advances
Topic: Melanoma Skin Cancer
Author: American Chemical Society
Published: 2010/08/12 - Updated: 2020/01/17
Contents: Summary - Introduction - Main - Related
Synopsis: Development of substance to enhance the visibility of skin cancer cells during scans. The five-year survival rate for melanoma is about 98 percent if detected early but can be as low as 15 percent when detected at an advanced stage. The hybrid scanner could enable doctors to detect melanoma, the most serious form of skin cancer, in its earliest and most curable stages.
Introduction
Advances toward earlier detection of melanoma skin cancer.
Main Digest
Scientists are reporting development of a substance to enhance the visibility of skin cancer cells during scans with an advanced medical imaging system that combines ultrasound and light.
The hybrid scanner could enable doctors to detect melanoma, the most serious form of skin cancer, in its earliest and most curable stages, the report in the monthly journal ACS Nano indicates.
Lihong Wang, Younan Xia, and colleagues point out that early diagnosis is key to improving survival in patients with melanoma.
The five-year survival rate for melanoma is about 98 percent if detected early but can be as low as 15 percent when detected at an advanced stage.
Existing imaging techniques for early detection of melanoma produce low-quality images, can "see" only a fraction of an inch below the skin, and use potentially harmful radioactive materials.
A promising new technique called photo-acoustic tomography (PAT) can overcome these problems.
The system shoots light into tumors, which slightly heats up the cancer cells and produces high frequency sound waves that provide images of the tumor.
But the PAT system lacks an optimal contrast agent that can easily enter skin cancer cells and make them visible.
The scientists developed such an agent by attaching a peptide (one of the building blocks of proteins) that targets skin cancer cells to gold "nanocages."
These hollow gold nanoparticles have a box-like shape and are barely 1/50,000th the width of a human hair.
When injected into mice with skin cancer, the nanocages improved the image quality of the cancer cells by three-fold compared to nanoparticles lacking the peptide.
The gold nanocages also show promise as a way to kill skin cancer cells using heat or anti-cancer drugs, they add.
Attribution/Source(s):
This quality-reviewed publication was selected for publishing by the editors of Disabled World due to its significant relevance to the disability community. Originally authored by American Chemical Society, and published on 2010/08/12 (Edit Update: 2020/01/17), the content may have been edited for style, clarity, or brevity. For further details or clarifications, American Chemical Society can be contacted at www.acs.org. NOTE: Disabled World does not provide any warranties or endorsements related to this article.
Page Information, Citing and Disclaimer
Disabled World is a comprehensive online resource that provides information and news related to disabilities, assistive technologies, and accessibility issues. Founded in 2004 our website covers a wide range of topics, including disability rights, healthcare, education, employment, and independent living, with the goal of supporting the disability community and their families.
Cite This Page (APA): American Chemical Society. (2010, August 12 - Last revised: 2020, January 17). Earlier Detection of Melanoma Advances. Disabled World. Retrieved September 10, 2024 from www.disabled-world.com/health/cancer/melanoma/detection-advances.php
Permalink: <a href="https://www.disabled-world.com/health/cancer/melanoma/detection-advances.php">Earlier Detection of Melanoma Advances</a>: Development of substance to enhance the visibility of skin cancer cells during scans.
Disabled World provides general information only. Materials presented are never meant to substitute for qualified medical care. Any 3rd party offering or advertising does not constitute an endorsement.