Mesothelioma: Symptoms and General Overview
Category Topic: Mesothelioma
Author: Disabled World
Updated/Revised Date: 2022/04/11
Contents: Summary - Introduction - Main - Subtopics - Publications
Synopsis: Information regarding pleural and peritoneum mesothelioma, a type of cancer caused by exposure to asbestos. In the U.S. asbestos is the major cause of malignant mesothelioma and has been considered indisputably associated with the development of mesothelioma. However, mesothelioma has been reported in some individuals without any known exposure to asbestos. If you have previously been exposed to asbestos, you should go see your doctor right away and explain your concerns. Even if it turns out that you do not have this type of cancer, it is better to be safe than sorry.
Introduction
Mesothelioma (malignant mesothelioma) is a rare form of cancer that develops from cells of the mesothelium, the tissue that lines your lungs, stomach, heart, and other organs is called mesothelium. Mesothelioma is most commonly caused by exposure to asbestos. A doctor uses imaging tests and a biopsy to tell the difference between malignant mesothelioma and lung cancer. Signs and symptoms of mesothelioma include shortness of breath due to pleural effusion (fluid between the lung and the chest wall), chest wall pain and constitutional signs such as unexplained weight loss.
Main Document
In the United States, asbestos is the major cause of malignant mesothelioma and has been considered indisputably associated with the development of mesothelioma. However, mesothelioma has been reported in some individuals without any known exposure to asbestos. In rare cases, mesothelioma has also been associated with irradiation, intrapleural thorium dioxide (Thorotrast), and inhalation of other fibrous silicates, such as erionite. Some studies suggest that simian virus 40 (SV40) may act as a cofactor in the development of mesothelioma. This has been confirmed in animal studies, but studies in humans are inconclusive.
- About 3,000 new cases of mesothelioma are diagnosed each year in the United States.
- The latency period between first exposure to asbestos and clinical disease is usually 20 to 40 years.
- The rate of mesothelioma in the United States increased from the 1970s to the early 1990s, but since then, it has leveled off and even gone down slightly.
- Based on data from the National Cancer Institute's SEER program, the relative 5-year survival rate for mesothelioma is between 5% and 10%. People diagnosed at a younger age tend to survive longer.
Mesothelium is Divided into Two Parts
- The first is the pleural, which lines the lungs. The pleura comprises an inner layer and an outer layer which slide over each other as you breathe. If mesothelioma develops in this area it is known as pleural mesothelioma and it causes the two layers to become thicker.
- The second is the peritoneum, which lines the abdomen, and it also has an inner layer and an outer layer. If the mesothelioma affects this area it is known as peritoneal mesothelioma and it also causes these layers to become thicker.
Symptoms of Mesothelioma
The symptoms of mesothelioma vary based on the region of your body affected by the cancer, these include:
- Shortness of breath
- Lumps of tissue under your chest skin
- Weight loss
- Dry cough
- Painful breathing
- Painful coughing
- Chest pain near the rib cage
The symptoms of peritoneal mesothelioma are:
- Weight loss
- Nausea
- Vomiting
- Abdominal pain
- Abdominal swelling
- Change in bowel habits (frequent diarrhea or constipation)
- Lumps of tissue in abdomen
Both types of mesothelioma can be very painful and lead to several undesirable symptoms. Pleural mesothelioma can cause breathlessness, coughing, and chest pain. It can also lead to pleural effusion, where lubricating fluid in the lungs becomes trapped between the inner and outer layers of the pleura. Peritoneal mesothelioma can lead to abdominal pain, bowel problems, and it's swelling in the abdomen.
Almost every case of mesothelioma is caused by exposure to asbestos. In the past, asbestos was a very popular construction material. However, as people became more knowledgeable, they learned about the dangers associated with this material. In particular, they discovered that the very fine fibers that make up asbestos are easily released when the material is handled.
If you have previously been exposed to asbestos, you should go see your doctor right away and explain your concerns. Even if it turns out that you do not have this type of cancer, it is better to be safe than sorry.
Other Diseases Related to the Exposure of Asbestos Fibers
Not all of these are deadly, but they all result in health damage and even damage to the quality of the patient's life. Most of these diseases can be predicted and treated during the time of asbestos exposure. Normally, your exposure to the dust and fibers of asbestos does not cause disease immediately. However, you need to protect yourself from being exposed just to make sure that you will not develop a medical condition related with the mineral.
The dust and fibers of asbestos are hazardous since these are tiny. In fact, a microscope is needed just to determine the type of asbestos fiber. Once they enter the body, there are two possible places where asbestos fibers go. When the fibers are breathed accidentally, they go to your lungs. If they are swallowed, they go to your stomach. Hence, the most common types of asbestos-related diseases occur in the human chest and lungs.
When the fibers of asbestos are viewed through a microscope, they appear sharp. If they get inside your body, they will destroy your tissues. It has been said that all levels of asbestos exposure are harmful to the body. This is because just one fiber can bring severe harm. The risk is greatest when you are constantly exposed to it. Medical experts say that the only way for you to hinder the development of asbestos-related health problems is to keep yourself from being exposed to its fibers.
Cancer diseases, which are linked with asbestos exposure, generally take two to four decades to develop. The whole duration is known as the "latency period." Compared to other asbestos-related diseases, pleural thickening occurs more often. There are some individuals who refer to their disease as "asbestosis." However, asbestosis is the specific term for one condition. For you to know what is affecting you precisely, you need the diagnosis of a specialist. The following are among the diseases that are brought about due to severe exposure to the fibers and dust of asbestos:
Lung Cancer and Other Types of Cancer Diseases
Epidemiological studies suggest that asbestos is one of the primary reasons for lung cancer related deaths. On the other hand, there are times when a specialist finds it hard to determine the cause of lung cancer. This is especially true when the patient smokes a lot. It has been discovered that exposure to asbestos, paired with smoking, increases the likelihood of developing lung cancer. Other types of asbestos-related cancer are larynx cancer; stomach cancer; and cancer of the rectum, colon, and ovaries.
Asbestosis
This is a type of pneumoconiosis. Asbestosis is the general reference for the damage occurring to the interior of your lung as a result of asbestos dust inhalation. Your lung consists of several alveoli, where carbon dioxide and oxygen are transported to and from your blood. When asbestos dust gets inside your lung, the walls of your alveoli are damaged.
Pleural plaques
These refer to the local scarring or thickening of the membrane lining your lungs. Although this type of illness is not that severe, it can be painful and discomforting. It can act as a precursor to another type of asbestos-related disease.
Pleural thickening
This happens when the pleural lining of your lung hardens due to the asbestos fibers found in your lungs. When the case is severe, it can lead to breathing difficulties.
Subtopics
Latest Publications From Our Mesothelioma Category
1: HXR9 Drug for Mesothelioma Cancer - Study reveals drug HRX9, that works by preventing cancer cells from avoiding apoptosis, shows promise for mesothelioma lung cancer.
2: Olive Leaf Compound Could Treat Malignant Mesothelioma - Researchers say a compound found in the leaves of olive trees could eventually form the basis of a new treatment for mesothelioma.
3: Total Ban on Asbestos in U.S. Sought by Steve McQueen's Widow - Barbara McQueen trying to convince federal law makers to finally ban the sale and use of asbestos in the United States.
4: Mesothelioma Cancer - A Slow and Silent Killer - Mesothelioma a once rare type of cancer primarily caused by exposure to asbestos is becoming a household name.
5: Pleural Mesothelioma Combination Therapy Shows Promise - Pleural mesothelioma patients who undergo lung-sparing surgery in combination with photodynamic therapy show superior overall survival than patients treated using conventional therapy of extrapleural pneumonectomy.
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