Olive Leaf Compound Could Treat Malignant Mesothelioma
- Publish Date: 2015/12/27
- Author: Cancer Monthy
Outline: Researchers say a compound found in the leaves of olive trees could eventually form the basis of a new treatment for mesothelioma.
Mesothelioma researchers in Italy say they have found "antiproliferative properties" in the compound that gives olive oil its bitter taste. The discovery may help slow the spread of the aggressive asbestos cancer. Surviving Mesothelioma has just posted an article on the new research.
Mesothelioma (malignant mesothelioma) is defined as a rare form of cancer that develops from cells of the mesothelium, the tissue that lines your lungs, stomach, heart, and other organs is called mesothelium. Mesothelioma is most commonly caused by exposure to asbestos. A doctor uses imaging tests and a biopsy to tell the difference between malignant mesothelioma and lung cancer. Signs and symptoms of mesothelioma include shortness of breath due to pleural effusion (fluid between the lung and the chest wall), chest wall pain and constitutional signs such as unexplained weight loss.
Carla Marchetti of the Consiglio Nazionale delle Ricerche in Genova and a team of Italian colleagues applied a phenylethanoid called oleuropein to mesothelioma cells in the lab.
According to a report in Evidence-Based Complementary and Alternative Medicine, oleuropein slowed the rapid cell growth and division that make mesothelioma so deadly.
Picture of an Olive tree leaf
"Data suggest that our oleuropein-enriched fraction from olive leaf extract could have pharmacological application in malignant mesothelioma anticancer therapy," writes Dr. Marchetti.
"It is always encouraging when a new compound - especially one that is naturally-derived - is found to have an impact on mesothelioma since conventional treatments have limited success," says Alex Strauss, Surviving Mesothelioma’s Managing Editor.
To read more about the oleuropein study and its potential impact on the future of mesothelioma treatment, see Olive Leaf Compound Could Lead to New Mesothelioma Treatment, available now on the Surviving Mesothelioma website (survivingmesothelioma.com).
Marchetti, C, et al, "Oleuropein-Enriched Olive Leaf Extract Affects Calcium Dynamics and Impairs Viability of Malignant Mesothelioma Cells", 2015, Evidence-Based Complementary and Alternative Medicine, Epub ahead of print, www.hindawi.com/journals/ecam/2015/908493/
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