Peritoneal Mesothelioma: Symptoms, Diagnosing, Treatment
Ian C. Langtree - Content Writer/Editor for Disabled World
Published: 2010/10/09 - Updated: 2023/02/01
Topic: Mesothelioma (Publications Database)
Page Content: Synopsis Introduction Main Item
Synopsis: Peritoneal Mesothelioma is a rare cancer of the abdominal lining usually associated with asbestos exposure and is regarded as universally fatal.
• Exposure to asbestos fibers can cause mesothelioma even years later.
• Peritoneal mesothelioma has two clinical types, which can be differentiated with the help of CT findings, the "dry" type and the "wet." It is classified as "dry" when there are multiple tiny masses or one dominant localized mass and generally little or no ascites.
Introduction
The processes leading to the development of peritoneal mesothelioma remain unresolved. However, it has been proposed that asbestos fibers from the lung are transported to the abdomen and associated organs via the lymphatic system. Additionally, asbestos fibers may be deposited in the gut after ingesting sputum contaminated with asbestos fibers. Approximately one-fifth to one-third of all mesotheliomas are peritoneal.
The U.S. Social Security Administration (SSA) has included Peritoneal Mesothelioma as a Compassionate Allowance to expedite a disability claim.
Main Item
Peritoneal mesothelioma has two clinical types, which can be differentiated with the help of CT findings, the "dry" type and the "wet." It is classified as "dry" when there are multiple tiny masses or one dominant localized mass and generally little or no ascites. The "wet" type has widespread small nodules, no dominant mass, and a presence of ascites. If the fluid is found, the process of eliminating it is through paracentesis; however, the analysis of this fluid has limited diagnostic significance. Normally, a definitive diagnosis may be obtained through tissue biopsy.
Exposure to asbestos fibers can cause mesothelioma even years later. There is evidence that family members and others living with people exposed to asbestos have an increased risk of developing mesothelioma and possibly other asbestos-related diseases. This risk may result from exposure to asbestos dust brought home on the clothing and hair of asbestos workers.
Symptoms
Symptoms of peritoneal mesothelioma include weight loss and cachexia, abdominal swelling, and pain due to ascites (a buildup of fluid in the abdominal cavity). Other symptoms of Peritoneal Mesothelioma may include bowel obstruction, blood clotting abnormalities, anemia, and fever. If cancer has spread beyond the mesothelium to other parts of the body, symptoms may include pain, trouble swallowing, or swelling of the neck or face. Other symptoms of peritoneal mesothelioma may include bowel obstruction, blood clotting abnormalities, anemia, and fever.
Diagnosing
Diagnosing Peritoneal Mesothelioma is often difficult; because the symptoms are often associated with other conditions. Diagnostic testing includes a review of the patient's medical history and a complete physical examination, including x-rays of the abdomen. Diagnostic imaging by CT scan and MRI suggests a diagnosis, but a definitive diagnosis is via tissue sampling by CT-directed biopsy or peritoneoscopy.
Treatment
Standard treatment for all but localized mesothelioma is generally not curative. However, radical resection is associated with a better prognosis and should be attempted when possible. Chemotherapy can be administered systemically or directly into the abdomen and is helpful as palliative treatment.
Delayed diagnosis of mesothelioma worsens its prognosis. In general, the prognosis of mesothelioma is poor, and most studies report a median survival of less than a year.
1 - HXR9 Drug for Mesothelioma Cancer - Study reveals drug HRX9, that works by preventing cancer cells from avoiding apoptosis, shows promise for mesothelioma lung cancer.
2 - Olive Leaf Compound Could Treat Malignant Mesothelioma - Researchers say a compound found in the leaves of olive trees could eventually form the basis of a new treatment for mesothelioma.
3 - Total Ban on Asbestos in U.S. Sought by Steve McQueen's Widow - Barbara McQueen trying to convince federal law makers to finally ban the sale and use of asbestos in the United States.
Page Information, Citing and Disclaimer
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Cite This Page (APA): Langtree, I. C. (2010, October 9 - Last revised: 2023, February 1). Peritoneal Mesothelioma: Symptoms, Diagnosing, Treatment. Disabled World. Retrieved December 13, 2024 from www.disabled-world.com/health/cancer/mesothelioma/peritoneal-mesothelioma.php
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