Urine Test for Diagnosis of Cancer

Author: University of Edinburgh
Published: 2011/06/13
Peer-Reviewed: N/A
Contents: Summary - Main - Related Publications

Synopsis: Cancers of the gut stomach and pancreas could be detected much sooner with a simple urine test. Simple test could hold key to early diagnosis of cancers - Cancers of the gut, stomach and pancreas could be detected much sooner with a simple urine test, research suggests.

Main Digest

Simple test could hold key to early diagnosis of cancers - Cancers of the gut, stomach and pancreas could be detected much sooner with a simple urine test, research suggests.

Cancers of the gut, stomach and pancreas could be detected much sooner with a simple urine test, research suggests.

Researchers at the University of Edinburgh have identified key proteins in the urine of patients with advanced cancers.

The findings could help the detection of these cancers in people who have not yet started to show symptoms of the disease.

This would enable patients to be diagnosed much earlier, leading to improved survival rates.

Only around 10 percent of patients with these cancers - known as cancers of the upper gastrointestinal tract - are still alive five years after diagnosis.

This is because such cancers, which tend to be aggressive, are often diagnosed at an advanced stage.

Dr Holger Husi, of the University of Edinburgh's Tissue Injury and Repair Group, said: "The aim of this work is to enable these cancers to be diagnosed much earlier. This would help us to treat the cancer before it has a chance to spread. The majority of these cancers are currently diagnosed late where no surgery is possible due to its advanced stage. Earlier diagnosis would mean that curative surgery or chemotherapy would be possible for more patients."

The research, published in the journal Proteomics-Clinical Applications, compared urine samples from patients with upper gastrointestinal cancers with urine samples from people who were cancer-free.

Scientists analyzed the samples to identify thousands of proteins. They then identified six particular proteins, which were present in 98 percent of the cancer cases but absent in almost 90 percent of samples from patients without cancer.

The researchers then narrowed molecules down to the two proteins - S100A6 and S1009 - most likely to appear in samples from patients with cancer but be absent from the other samples.

The scientists now intend to see whether people with early stage cancers, which have not yet been diagnosed, have the same levels of proteins present.

This would involve analyzing samples from at least 1,000 volunteers and tracking the participants over a number of years to identify those who are then later diagnosed with upper gastrointestinal cancers.

📢 Discover Related Topics


👍 Share This Information To:
𝕏.com Facebook Reddit

Page Information, Citing and Disclaimer

Disabled World is an independent disability community founded in 2004 to provide disability news and information to people with disabilities, seniors, their family and/or carers. See our homepage for informative reviews, exclusive stories and how-tos. You can connect with us on social media such as X.com and our Facebook page.

Permalink: <a href="https://www.disabled-world.com/health/cancer/treatment/urine-test.php">Urine Test for Diagnosis of Cancer</a>

Cite This Page (APA): University of Edinburgh. (2011, June 13). Urine Test for Diagnosis of Cancer. Disabled World. Retrieved February 24, 2024 from www.disabled-world.com/health/cancer/treatment/urine-test.php

Disabled World provides general information only. Materials presented are never meant to substitute for qualified professional medical care. Any 3rd party offering or advertising does not constitute an endorsement.