Where Does Consciousness Come From? Neural Roots of Consciousness
Author: Public Library of Science
Published: 2009/03/17 - Updated: 2025/11/23
Publication Type: Research, Study, Analysis
Category Topic: Neurological Disorders - Related Publications
Page Content: Synopsis - Introduction - Main - Insights, Updates
Synopsis: This research article, published in PLoS Biology and authored by neuroscientists at INSERM including Dr. Gaillard and Lionel Naccache, presents groundbreaking findings about how consciousness emerges in the human brain through the convergence of four distinct neural processes occurring approximately 300 milliseconds after perception. The study gains its authority from rigorous experimental methodology using intra-cerebral recordings from epilepsy patients who had already undergone electrode implantation for medical purposes, allowing researchers to measure brain activity with exceptional spatial and temporal precision while participants viewed masked and unmasked words.
Rather than identifying a single "seat of consciousness," the research supports the Global Workspace Theory by demonstrating that conscious awareness results from distributed, coherent activation across brain regions - a finding particularly relevant for understanding neurological conditions affecting consciousness in people with brain injuries, cognitive impairments, or age-related changes. The work moves beyond the search for one definitive neural marker and instead reveals that consciousness represents a complex pattern of synchronized brain activity, offering insights that could eventually inform diagnostic approaches and therapeutic interventions for disorders of consciousness affecting patients across diverse populations - Disabled World (DW).
Introduction
Consciousness arises as an emergent property of the human mind. Yet basic questions about the precise timing, location and dynamics of the neural event(s) allowing conscious access to information are not clearly and unequivocally determined.
Some neuroscientists have even argued that consciousness may arise from a single "seat" in the brain, though the prevailing idea attributes a more global network property.
Main Content
Do the neural correlates of consciousness correspond to late or early brain events following perception? Do they necessarily involve coherent activity across different regions of the brain, or can they be restricted to local patterns of reverberating activity? A new paper, published in this week's PLoS Biology, suggests that four specific, separate processes combine as a "signature" of conscious activity. By studying the neural activity of people who are presented with two different types of stimuli - one which could be perceived consciously, and one which could not - Dr. Gaillard of INSERM and colleagues, show that these four processes occur only in the former, conscious perception task.
This new work addresses the neural correlates of consciousness at an unprecedented resolution, using intra-cerebral electro-physiological recordings of neural activity. These challenging experiments were possible because patients with epilepsy who were already undergoing medical procedures requiring implantation of recording electrodes agreed to participate in the study. The authors presented them with visually masked and unmasked printed words, then measured the changes in their brain activity and the level of awareness of seeing the words. This method offers a unique opportunity to measure neural correlates of conscious access with optimal spatial and temporal resolutions. When comparing neural activity elicited by masked and unmasked words, they could isolate four converging and complementary electro-physiological markers characterizing conscious access 300 ms after word perception.
All of these measures may provide distinct glimpses into the same distributed state of long-distance reverberation. Indeed, it seems to be the convergence of these measures in a late time window (after 300 ms), rather than the mere presence of any single one of them, which best characterizes conscious trials.
"The present work suggests that, rather than hoping for a putative unique marker - the neural correlate of consciousness - a more mature view of conscious processing should consider that it relates to a brain-scale distributed pattern of coherent brain activation," explained neuroscientist Lionel Naccache, one of the authors of the paper.
The late ignition of a state of long distance coherence demonstrated here during conscious access is in line with the Global Workspace Theory, proposed by Stanislas Dehaene, Jean-Pierre Changeux, and Lionel Naccache.
Gaillard R, Dehaene S, Adam C, Clemenceau S, Hasboun D, et al. (2009) Converging intracranial markers of conscious access. PLoS Biol 7(3).