Restless Legs Syndrome Causes, Symptoms, and Treatment
Author: Disabled World (DW)
Updated/Revised Date: 1 Aug 2026
Table of Contents:
Synopsis - Definition - About This Section - FAQs - Publications - Subtopics
Synopsis
Learn about restless legs syndrome, a neurological sleep disorder, including its uncomfortable leg sensations, common causes, symptoms, and treatment approaches.
At a Glance
- 1 - RLS is also known as Wittmaack-Ekbom's syndrome and impacts about 8 to 10 percent of the US population.
- 2 - A family history is seen in about half of cases, which suggests a genetic form of the disorder.
- 3 - Many people with RLS also have periodic limb movements of sleep, jerks that occur every 20 to 30 seconds through the night.
- 4 - Neurologic conditions linked to RLS include Parkinson disease, spinal stenosis, lumbosacral radiculopathy, and Charcot-Marie-Tooth disease type 2.
Topic Definition
- Restless Legs Syndrome
Restless legs syndrome is a disorder of the nervous system that produces an irresistible urge to move the legs, and sometimes the arms or torso, in order to relieve uncomfortable sensations often described as creeping, itching, pulling, or crawling. Because these feelings tend to appear when a person is sitting or lying down and trying to relax, the condition regularly interferes with falling and staying asleep, which is why it is also classed as a neurological sleep disorder. Moving the affected limb eases the sensations, at least temporarily, and relief lasts as long as the movement continues. Although there is no cure, symptoms can often be managed through treating any underlying causes and through lifestyle changes, and a diagnosis does not signal the onset of another neurological disease such as Parkinson's.
Overview
Restless legs syndrome (RLS) is a disorder of the part of the nervous system that affects movements of the legs. Because it usually interferes with sleep, it also is considered a neurological sleep disorder. RLS impacts about 8-10% of the US population. Men and women are impacted equally. It may begin at any age, even in infants and young children. Most people who are affected severely are middle-aged or older.
Restless leg syndrome (RLS) is a condition in which your legs feel extremely uncomfortable while you're sitting or lying down. It makes you feel like getting up and moving around. When you do so, the unpleasant feeling of restless leg syndrome temporarily goes away.
Restless legs syndrome (RLS, Wittmaack-Ekbom's syndrome, or sometimes, but inaccurately, referred to as Nocturnal myoclonus) is a condition that is characterized by an irresistible urge to move one's body to stop uncomfortable or odd sensations. It most commonly affects the legs, but can also affect the arms or torso. Moving the affected body part modulates the sensations, providing temporary relief. RLS causes a sensation in the legs or arms that can most closely be compared to a burning, itching, or tickling sensation in the muscles.
Some researchers estimate that RLS impacts as many as 12 million Americans. However, others estimate a much higher occurrence because RLS is thought to be under-diagnosed and, in some cases, misdiagnosed. A family history of the condition is seen in approximately 50 percent of such cases, suggesting a genetic form of the disorder. Some pregnant women experience RLS, especially in their last trimester. For most of these women, symptoms usually disappear within 4 weeks after delivery.
Restless legs syndrome can cause difficulty in falling or staying asleep, which can be one of the complaints of the syndrome. Some people who have RLS also have periodic limb movements of sleep (PLMS). These are jerks that occur every 20 to 30 seconds on and off throughout the night.
The most distinctive or unusual aspect of the condition is that lying down and trying to relax activates the symptoms. As a result, most people with RLS have difficulty falling asleep and staying asleep. Left untreated, the condition causes exhaustion and daytime fatigue.
Restless legs syndrome means to have a strong urge to move your legs, which you may not be able to resist. The need to move is often accompanied by uncomfortable sensations. Some words used to describe these sensations include: creeping, itching, pulling, creepy crawly, tugging, or gnawing.
Treatment for RLS
Apart from preventing the underlying causes, generally no method of preventing RLS has been established or studied. If RLS is due to specific treatable causes (specific medications or treatable conditions), then treatment of those causes may also remove or reduce RLS. Otherwise, medical responses focus on treating the condition, either symptomatically or by targeting lifestyle changes and bodily processes capable of modifying its expression or severity.
Treatment of restless legs syndrome involves identifying the cause of symptoms when possible. The treatment process is designed to reduce symptoms, including decreasing the number of nights with RLS symptoms, the severity of RLS symptoms and nighttime awakenings. Improving the quality of life is another goal in treatment.
RLS symptoms get better when you move your legs. The relief can be complete or only partial, but typically starts very soon after starting an activity. Relief persists as long as the motor activity continues. For those with mild to moderate symptoms, prevention is key, and many physicians suggest certain lifestyle changes and activities to reduce or eliminate symptoms.
Decreased use of caffeine, alcohol, and tobacco may provide some relief. Physicians may propose that certain individuals take supplements to correct deficiencies in iron, folate, and magnesium. Studies also have shown that maintaining a regular sleep pattern can reduce symptoms.
Restless Legs Syndrome Facts and Statistics
- Restless legs syndrome may affect up to 10% of the U.S. population.
- Nearly half of people with RLS also have a family member with the condition.
- Neurologic conditions linked to RLS include Parkinson disease, spinal cerebellar atrophy, spinal stenosis, lumbosacral radiculopathy and Charcot-Marie-Tooth disease type 2.
- Restless legs syndrome affects both sexes, but is more common in women and may begin at any age, even in young children. Most people who are impacted severely are middle-aged or older.
- RLS is even more common in individuals with iron deficiency, pregnancy and end-stage renal disease. The National Sleep Foundation's 1998 Sleep in America poll showed that up to 25 percent of pregnant women developed RLS during the third trimester.
- Approximately 80 to 90% of people with RLS also have periodic limb movement disorder (PLMD), which causes slow "jerks" or flexions of the affected body part. These occur during sleep (PLMS - periodic limb movement while sleeping) or while awake (PLMW - periodic limb movement while waking).
Conclusion:
RLS is generally a lifelong condition for which there is no cure. Nevertheless, current therapies can control the disorder, minimizing symptoms and increasing periods of restful sleep. Symptoms may gradually worsen with age, although the decline may be somewhat faster for individuals who also suffer from an associated medical condition. In addition, some individuals have remissions, periods in which symptoms decrease or disappear for days, weeks, or months, although symptoms usually eventually reappear. A diagnosis of RLS does not indicate the onset of another neurological disease, such as Parkinson's disease.
Frequently Asked Questions
Does restless legs syndrome go away on its own
RLS is generally a lifelong condition without a cure, though some people have remissions where symptoms fade for days, weeks, or months before returning.
Can pregnancy cause restless legs syndrome
Yes, some pregnant women develop RLS, especially in the third trimester, and symptoms usually disappear within about four weeks after delivery.
What is the difference between RLS and periodic limb movement disorder
RLS is an urge to move the legs while awake, while periodic limb movement disorder causes involuntary jerks that mainly happen during sleep, and the two often occur together.
Can children develop restless legs syndrome
Yes, RLS may begin at any age, including in infants and young children, although the most severely affected people tend to be middle aged or older.
Are there lifestyle changes that ease restless legs syndrome
Reducing caffeine, alcohol, and tobacco, keeping a regular sleep pattern, and correcting iron, folate, or magnesium deficiencies may help relieve symptoms.
Is restless legs syndrome linked to iron deficiency
Yes, RLS is more common in people with iron deficiency, and physicians may suggest supplements to correct that and other deficiencies.
Does restless legs syndrome affect men and women differently
RLS affects both sexes but is more common in women, and it can begin at any age with the most severe cases usually appearing in middle age or later.
Curated and edited by Ian C. Langtree, Founder & Editor-in-Chief, Disabled World. This section is maintained by the Disabled World editorial team.
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