Clinical Trials: How Medical Research Studies Work: Publications and Documents
Summary
The Clinical Trials: Availability, Volunteers, Drug Research section of Disabled World (DW) offers a range of publications relevant to individuals with disabilities, seniors, and anyone interested in medical advancements. These resources include information on current clinical trials, opportunities for volunteer participation, and insights into ongoing drug research. Articles cover topics such as new treatments for specific conditions, the development of assistive technologies, and research into the efficacy of various therapies. The papers and articles are often peer-reviewed or sourced from reputable institutions, providing valuable, helpful, and interesting knowledge that can inform decisions about healthcare options, increase understanding of medical research, and offer hope through the exploration of innovative solutions.Searching the Database
The data table below lists items that may have been updated or revised, but the table defaults to sorting by descending publication date; you can search and sort by clicking column headers (JavaScript required). Items in this category are also distributed via our Clinical Trials: How Medical Research Studies Work RSS feed.
| Title and Description | Ed | Publish Revised |
|---|---|---|
| Phase 1 Clinical Trial for Intranasal COVID-19 Vaccine Against Emerging SARS-CoV-2 Variants A new nasal candidate vaccine could provide enhanced breadth of protection against emerging SARS-CoV-2 variants. | ||
| Promoting Health Equity: Integrating Nursing Home Residents into Clinical Trials Commentary focuses on the importance of including nursing home residents, a population with significant medical complexity, in clinical trials. | ||
| The PALACE Study Looks at Reducing the Penicillin Allergy Label Many low-risk patients with a penicillin allergy were able to have their penicillin allergy label removed through a procedure known as direct oral challenge as part of a world-first multicenter randomized control trial known as the Penicillin Allergy Clinical Decision Rule (PALACE) study. | ||
| mRNA Universal Influenza Vaccine Clinical Trial A clinical trial of an experimental universal influenza vaccine has begun enrolling volunteers at Duke University in Durham, North Carolina. | ||
| Disabled Commonly Excluded From Clinical Trial Eligibility Despite constituting the largest minority group in the U.S. and expressing interest in participating in clinical trials, people with disabilities remain excluded. | ||
| New Multiple Sclerosis Treatment Clinical Trial Begins Enrollment Clinical trial of Autologous Hematopoietic Stem Cell Transplantation versus Best Available Therapy for Multiple Sclerosis (BEAT-MS) begins enrollment. | ||
| Clinical Trial Recognizes Needs of Severely Disabled MS Patients New clinical trial testing disease modifying drug for multiple sclerosis (MS) first in the world to recognize importance of wheelchair users retaining use of their hands. | ||
| Intensity Therapeutics Human Cancer Clinical Trial Update Intensity Therapeutics a private biotech firm is way ahead of big pharma and universities with human cancer immuno oncology clinical trials. | ||
| Fighting Cancer As Much As Possible: Why Patients Join Phase 1 Clinical Trials The importance of early stage trials is increasing because of the pressing need for new drugs. | ||
| Pediatric Neural Tumor Shrinkage Shown in Selumetinib Clinical Trial Early-phase clinical trial of selumetinib in children with common genetic disorder neurofibromatosis type 1 (NF1) and plexiform neurofibromas. | ||
| Antidote: A Digital Health Company on a Mission Antidote matches the right patients with the right clinical trials, helping medical researchers make faster progress, and offering new treatment options to patients. | ||
| Evaluating FDA Approach to Cancer Clinical Trials U.S. FDA is committed to meet needs of patients and health care communities in prevention, diagnosis, and treatment of cancer. | ||
| AST-OPC1 Clinical Study for Spinal Cord Injury Patients Asterias Biotherapeutics AST-OPC1 treatment for spinal cord injury patients shown to help paralyzed patients regain function in arms and hands. | ||
| UK Clinical Trial to Test Treatments for Vitiligo We are looking for people who have at least one patch of vitiligo that has appeared or worsened over the past year. | ||
| Largest Autism Clinical Trial in History Extends Recruitment Target Mental Imagery Therapy for Autism (MITA), an early-intervention application for children with ASD, is currently being validated in the clinical trial. | ||
| Clinical Trials of Robotic Legs Help Patients Walk Again Clinicians and engineers at University of Kent carrying out first clinical trials of robotic legs for patients. | ||
| Clinical Trials: Seeking Female Diversity It is important for more women, particularly those of diverse ethnicities, to take part in clinical trials. | ||
| First US Clinical Trial for Lewy Body Dementia HEADWAY-DLB is a phase 2b multi-center, double-blind, placebo-controlled study to evaluate investigational medicine RVT-101 for dementia with Lewy bodies. | ||
| SCI Researcher Seeking Volunteers with Spinal Cord Injuries Spinal cord injury researcher is seeking participants with spinal cord injuries for the final phase of her doctoral research. | ||
| Study to Control and Prevent Urinary Symptoms in People with Spinal Cord Injury and Disease United Spinal Association recruiting people with spinal cord injury and disease for a study to control and prevent urinary symptoms. | ||
| FDA Grants Therapy Designation for Ocrelizumab in Primary Progressive MS FDA grants breakthrough therapy designation for the investigational medicine Ocrelizumab (OCREVUS) for treatment of primary progressive multiple sclerosis (PPMS). | ||
| Argus II Bionic Eye Clinical Trial Results Results of 3 year clinical trial study of retinal implant known as the Argus II bionic eye for people blinded by retinitis pigmentosa. | ||
| Early Clinical Trials Find Powdered Measles Vaccine Safe Measles vaccine made of fine dry powder delivered with puff of air triggered no adverse side effects in early human testing and it is likely effective. | ||
| ELND005 Clinical Study in Youth with Down Syndrome Results Transition announce results of clinical study of neuropsychiatric drug candidate ELND005 in young adults with Down syndrome. | ||
| IMC-1 Fibromyalgia Treatment Reduces Pain and Symptoms IMC-1 oral medication proves highly effective at reducing pain and other symptoms of fibromyalgia (FM) in patients in a recent clinical trial. | ||
| Pain Relief for Knee Osteoarthritis with Traumeel and Zeel Intra-articular Injections This study supports clinical feedback from healthcare professionals regarding positive outcomes with Traumeel and Zeel injections in knee osteoarthritis. | ||
| Glyder Device Offers Non-Fusion Option for Facet Pain Glyder Facet Restoration Device: a minimally invasive, non-fusion polymer disc implant that treats chronic lumbar facet joint pain while preserving spinal motion. | ✓ ✓ | |
| Human Clinical Trial of Ebola Vaccine Started Researchers at NIAID are conducting early phase trial to evaluate VSV-ZEBOV Ebola virus vaccine. | ||
| Clinical Trial of Rett Syndrome Drug Shows Promise Clinical trial finds a growth factor known as IGF1 can help treat some symptoms of Rett syndrome. | ||
| Cerebral Palsy Clinical Trial Using Cord Blood Stem Cell Therapy Recruiting efforts are underway to enroll children between the ages of 2 and 10 diagnosed with cerebral palsy in an FDA regulated clinical trial using stem cell therapy. | ||
| EPA Experiments Seek to Harm People States AAPS Association of American Physicians and Surgeons states EPA is soliciting senior Americans to volunteer for experiments where the purpose is to harm people. | ||
| Drugs Show Promise Against Aggressive Medulloblastoma Childhood Brain Tumor Study identified with potential to improve treatment of a high-risk childhood brain tumor are now part of pediatric clinical trial. | ||
| Therapeutic Target for Treating Huntington's and Parkinson's Disease Research from Western University has revealed a possible new target for treating movement disorders such as Huntington's disease (HD) and Parkinson's disease. | ||
| BrainGate Trial to Restore Movement for People with Paralysis Experts in muscle stimulation technology and brain-computer interfaces working to restore movement for people with paralysis. | ||
| Autism Clinical Trial Regarding Cord Blood Stem Cells First FDA approved clinical trial to evaluate use of child's own cord blood stem cells to treat patients with autism. | ||
| Landmark Clinical Study in Spinal Cord Injury Phase 2 clinical trial of SUN13837 an investigational medication developed to improve neurological function in patients with newly diagnosed acute spinal cord injury. | ||
| Oral Laquinimod Drug May Ease Multiple Sclerosis Disability Laquinimod has been shown to be effective in treating the progression of Multiple Sclerosis (MS) for patients with relapsing remitting forms of the disease. | ||
| New HIV Vaccine - Human Trials Initiated The trial funded by the Wellcome Trust called MUCOVAC2 is evaluating a vaccine that contains the HIV trimeric gp140 protein CN54 representative of Clade C strains of the virus. | ||
| Artificial Pancreas System Clinical Trials - FDA Outlines Flexible Approaches Draft guidance designed to help investigators and manufacturers to develop and seek approval for artificial pancreas device systems to treat type 1 diabetes. | ||
| New Cancer Vaccine Receives Approval for Clinical Tests and Secures Substantial Financing Immunicum which is developing cancer vaccines has received approval to test the vaccine on humans for the first time. | ||
| ACTEMRA Monotherapy Improves Symptoms of Rheumatoid Arthritis Data from Phase III clinical trials in rheumatoid arthritis patients who received ACTEMRA (tocilizumab) as monotherapy and those who received ACTEMRA plus antirheumatic drug (DMARD), including methotrexate (MTX). | ||
| Examining Meds to Treat Social Withdrawal in Autism Children and adults with social withdrawal due to Fragile X syndrome or autism may benefit from an experimental drug under study. | ||
| Investigational Treatment for SCI and TBI Acorda plans to study AC105 as an acute treatment for patients who have suffered neurological trauma such as spinal cord injury and traumatic brain injury. | ||
| Trial of SBC-102 in Adults with Lysosomal Acid Lipase Deficiency Clinical study to evaluate the safety, tolerability, and pharmacokinetics of SBC-102 as an enzyme replacement therapy for cholesteryl ester storage disease (CESD). | ||
| First Ever Clinical Trial Approved for Spinal Muscular Atrophy Families of Spinal Muscular Atrophy approval from FDA to commence a Phase I safety study for RG3039 formerly called Quinazoline495 developed for Spinal Muscular Atrophy. | ||
| Encouraging Results of SAR 1118 Dry Eye Disease Study We are encouraged by the clinical effects of SAR 1118 in improving both signs and symptoms of dry eye. | ||
| Joining a Clinical Trial Clinical trials are research studies in which people help doctors find ways to improve health and cancer care. | ||
| Clinical Trial of SB623 Cell Therapy for Stroke Disability Phase 1/2a clinical trial testing safety and efficacy of Allogeneic cell therapy SB623 on patients suffering from stable deficits resulting from previous stroke injuries. | ||
| Traumatic Brain Injury Clinical Trial Collaboration NeuroVive announced agreement with European Brain Injury Consortium to conduct clinical trial of NeuroSTAT for neuro-protection in patients with traumatic brain injury (TBI). | ||
| Clinical Trial to Find Best Way of Treating Arm Pain More than 500 people suffering from lower arm pain are to take part in a new UK-wide clinical trial. | ||
| Neuralstem ALS Clinical Trial Update Neuralstem reports the progress of ongoing Phase I human clinical trial of spinal cord stem cells in the treatment of Amyotrophic Lateral Sclerosis (ALS), or Lou Gehrig's disease. | ||
| Clinical Trial For Rett Syndrome Launched Study marks the emergence of disease-modifying treatments for autism spectrum disorders. | ||
| Can Aspirin Prolong a Healthy Life The Aspirin in Reducing Events in the Elderly study will assess whether aspirin can prolong life and if it can prolong a life free of physical disability and dementia for healthy older people. | ||
| Curemark Adds Two Autism Trial Sites in California Curemark announces it has added two sites in California to its Phase III clinical trial program for CM-AT autism treatment. | ||
| Parents Experience Difficulty with Pediatric Cancer Trials Consent Process Compared with adult cancer patients parents of children with cancer were more likely to be dissatisfied with consent process for participating in clinical trials. | ||
| Reovirus Appears to Have a Redemptive Quality - The Ability to Kill Cancer Reovirus that can cause coughing and mild diarrhea appears to have a major redemptive quality - the ability to kill cancer. | ||
| Novartis Once-Yearly Reclast Preserves Bone Mass and Fracture Protection in Postmenopausal Osteoporosis Long-term data show novartis once-yearly reclast preserves bone mass and provides fracture protection in postmenopausal osteoporosis. | ||
| Successful Phase 2 Trial of Gene Therapy for Parkinson's Disease New Details Presented at the World Parkinson Congress on Neurologix's Successful Phase 2 Trial of Gene Therapy for Parkinsons Disease. | ||
| Genital Herpes Vaccine Ineffective in Women An experimental vaccine intended to prevent genital herpes disease in women although generally safe and well-tolerated proved ineffective. | ||
| Abatacept Ineffective in Non-life Threatening Lupus Treatment Abatacept found ineffective in treatment of non-life threatening lupus further trials needed to determine clinical application of drug in SLE. | ||
| Drug Trial Offers Hope for Heart Attack Patients New findings from major drug trial a step closer to developing a drug which could prevent thousands of deaths from heart attacks. | ||
| First Clinical Trials Successfully Completed on Potent New hepatitis C Drug First clinical trials on a new drug being developed to treat infections caused by Hepatitis C virus successfully completed. | ||
| Success Stops Apixaban Drug Trial Evidence of success of apixaban in prevention of stroke in patients with atrial fibrillation who are unsuitable for treatment of warfarin. | ||
| Spinal Cord Injury Stem Cell Trial - Neuralstem Files FDA Application Phase I safety clinical trial for chronic spinal cord injury with its spinal cord stem cells. | ||
| Comparing Tapentadol Extended Release Tablets to Oxycodone Controlled Release Tablets Study found tapentadol ER was associated with a lower overall incidence of gastrointestinal adverse events than oxycodone CR. | ||
| Clinical Trial Matching Service for Alzheimer's The Alzheimer's Association announced today the launch of Alzheimer's Association TrialMatch. | ||
| Trial of Gene Therapy for Parkinson's Disease Successful Neurologix Announces Successful Phase 2 Trial of Gene Therapy for Parkinsons Disease. | ||
| Curemark Begins Autism Trials at Two More Sites Curemark is a drug research and development company focused on the treatment of neurological and other diseases. | ||
| New Hepatitis C Drug Trials Begin Clinical trials have started on a new drug which is being developed to treat infections caused by Hepatitis C virus. | ||
| Total Spine Arthroplasty System Trial First approved clinical study for a Total Spine Arthroplasty system in the U.S.. | ||
| MS Patients Receiving Alemtuzumab Remain Free of Clinically-Active Disease Multiple sclerosis (MS) trial showed 71 percent of alemtuzumab treated patients remain free of clinically-active disease for three years. | ||
| Cordis Trial of New Stent Graft System First patients enrolled in cordis trial of new stent graft system to treat abdominal aortic aneurysm. | ||
| Stroke Treatment Passes Safety Stage of Clinical Trial Clinical research trial of a new treatment to restore brain cells damaged by stroke has passed an important safety stage. | ||
| VLP Pandemic Influenza Vaccine Study - Novavax Immunogenicity data from Pivotal 2009 A/H1N1 VLP pandemic influenza vaccine study in Mexico. | ||
| Stroke Clinical Trial in UK First-in-man clinical trial with its ReN001 stem cell therapy for stroke. | ||
| TOPICA'S Luliconazole IND to Begin Clinical Trials in Onychomycosis Trial for use of luliconazole in patients with onychomycosis nail and nail bed fungal infections. | ||
| Treatment of Advanced Waldenstrom's Macroglobulinemia - Clinical Trial Positive Phase 2 Study Results of Perifosine as Single Agent for Treatment of Advanced Waldenstroms Macroglobulinemia. |
Key: the first check mark indicates the publication carries an editor's note; the second indicates a footnote.
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