OxyContin - Information Uses and Side Effects

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Main Digest

Generic Name: oxycodone (ox i KOE done)

Brand Names: ETH-Oxydose, OxyContin, Oxyfast, OxyIR, Percolone, Roxicodone, Roxicodone Intensol

OxyContin is in a group of drugs called narcotic pain relievers. It is similar to morphine. OxyContin tablets are used to treat moderate to severe pain. The extended-release form of this medication is for around-the-clock treatment of pain relief associated with injuries, bursitis, dislocations, fractures, neuralgia, arthritis, lower back pain, and pain associated with cancer.

OxyContin was the best-selling non-generic narcotic pain reliever in the U.S.; in 2002, over 7.2 million prescriptions were written for it, for total sales of $1.5 billion.

Oxycodone is an opioid analgesic medication synthesized from opium-derived thebaine. It was developed in 1916 in Germany, as one of several new semi-synthetic opioids with several benefits over the older traditional opiates and opioids: morphine, diacetylmorphine (heroin), and codeine.

Oxycodone can be combined with inert binders (e.g., OxyContin); with paracetamol, also known as acetaminophen (e.g., Percocet, Endocet, Tylox, and Roxicet); with aspirin (e.g., Percodan, Endodan, Roxiprin); and with ibuprofen (Combunox).

OxyContin is currently available in 5 mg (blue) tablets in Canada and the U.K.; 10 mg (white) in Canada, the U.S., and the U.K.; 15 mg (grey) in the U.S.; 20 mg (pink) in Canada, the U.S., and the U.K.; 30 mg (brown) in the U.S.; 40 mg (tan) in Canada, the U.S., and the U.K.; 60 mg (red) in the U.S.; and 80 mg (green) in Canada, the U.S., and the U.K.

Oxycodone can be administered orally, intranasally, via intravenous/intramuscular/subcutaneous injection or rectally. The bio-availability of oral administration averages 60-87%, with rectal administration yielding the same results; intranasal varies between 55-70%.

The most commonly reported effects include constipation, fatigue, dizziness, nausea, lightheadedness, headache, dry mouth, anxiety, pruritus, euphoria, and diaphoresis.

There is a high risk of experiencing severe withdrawal symptoms if a patient discontinues oxycodone abruptly. Therefore therapy should be gradually discontinued rather than abruptly discontinued. People who use oxycodone in a hazardous or harmful fashion are at even higher risk of severe withdrawal symptoms as they tend to use higher than prescribed doses. The symptoms of oxycodone withdrawal are the same as for other opiate based painkillers and may include "anxiety, nausea, insomnia, muscle pain, fevers, and other flu like symptoms.

OxyContin may be habit-forming and should be used only by the person it was prescribed for. OxyContin should never be shared with another person, especially someone who has a history of drug abuse or addiction.

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