Skip to main content
Accessibility  |  About  |  Contact  |  Privacy  |  Terms

Artificial Intelligence Helps Diagnose Cardiac Infections

  • Published: 2009-09-14 : Mayo Clinic.
  • Synopsis: Software designed to mimic the human brain may help diagnose cardiac infections without invasive exam.

Main Document

Mayo Clinic researchers say that "teachable software" designed to mimic the human brain may help them diagnose cardiac infections without an invasive exam. Those findings are being presented today at the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) in San Francisco.

Mayo Clinic researchers say that "teachable software" designed to mimic the human brain may help them diagnose cardiac infections without an invasive exam. Those findings are being presented today at the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) in San Francisco.

Endocarditis "an infection involving the valves and sometimes chambers of the heart "can be a problem in patients with implanted medical devices. It is serious and can be deadly. The mortality rate can be as high as one in five, even with aggressive treatment and removal of the device. With additional complications, the mortality could be over 60 percent. Diagnosis usually requires transesophageal echocardiography, an invasive procedure that also has risks. It involves use of an endoscope and insertion of a probe down the esophagus.

The software program is called an "artificial neural network" (ANN) because it mimics the brain's cognitive function and reacts differently to situations depending on its accumulated knowledge. That knowledge or training is provided by researchers, similar to how a person would "train" a computer to play chess, by introducing it to as many situations as possible. In this case, the ANN underwent three separate "trainings" to learn how to evaluate the symptoms it would be considering.

"If, through this novel method, we can help determine a percentage of endocarditis diagnoses with a high rate of accuracy, we hope to save a significant number of patients from the discomfort, risk and expense of the standard diagnostic procedure," says M. Rizwan Sohail, M.D., a Mayo Clinic infectious diseases specialist and leader of the study.

The team studied 189 Mayo patients with device-related endocarditis diagnosed between 1991 and 2003. The ANN was tested retrospectively on the data from these cases. When tested on cases with known diagnosis of endocarditis, the best-trained ANN was correct most of the time (72 of 73 implant-related infections and 12 of 13 endocarditis cases) with a confidence level greater than 99 percent.

Researchers say that, when used on an overall sample that included both known and unknown cases, the ANN accurately excluded endocarditis in at least half of the cases, thus eliminating half the cohort from a needless invasive procedure.

The research team included Loai Saadah, Pharm.D.; Tawam-Johns Hopkins Medicine, United Arab Emirates; and Daniel Uslan, M.D.; Paul Friedman, M.D.; David Hayes, M.D.; Walter Wilson, M.D.; James Steckelberg, M.D.; and Larry Baddour, M.D.; all of Mayo Clinic. The authors declared no conflicts of interest.

About Mayo Clinic

Mayo Clinic is the first and largest integrated, not-for-profit group practice in the world. Doctors from every medical specialty work together to care for patients, joined by common systems and a philosophy of "the needs of the patient come first." More than 3,300 physicians, scientists and researchers and 46,000 allied health staff work at Mayo Clinic, which has sites in Rochester, Minn., Jacksonville, Fla., and Scottsdale/Phoenix, Ariz. Collectively, the three locations treat more than half a million people each year.

Similar Topics

1 : Metabolomics - Promising Tool for Advancing in Treatment Personalization of Oncological Patients : Bentham Science Publishers.
2 : Effects of Genetic Engineering : Disabled World.
3 : Majority in Favor of Spinal Muscular Atrophy (SMA) Screening : University of Warwick.
4 : New Approach to Studying Chromosomes' Centers May Reveal Link to Down Syndrome and More : Michigan Medicine - University of Michigan.
5 : Drinking Glasses Can Contain Potentially Harmful Levels of Lead and Cadmium : University of Plymouth.
From our Medical Research section - Full List (159 Items)

Submit disability news, coming events, as well as assistive technology product news and reviews.


Loan Information for low income singles, families, seniors and disabled. Includes home, vehicle and personal loans.


Famous People with Disabilities - Well known people with disabilities and conditions who contributed to society.


List of awareness ribbon colors and their meaning. Also see our calendar of awareness dates.


Blood Pressure Chart - What should your blood pressure be, and information on blood group types/compatibility.





1 : Urine and Blood Tests Can Indicate Autism in Children
2 : Newborns Who Experience Stroke Regain Language Function in Opposite Side of Brain
3 : Cognition and Emotion Play a Role in Predicting Quality of Children's Friendships
4 : Metabolomics - Promising Tool for Advancing in Treatment Personalization of Oncological Patients

Citation


Disclaimer: This site does not employ and is not overseen by medical professionals. Content on Disabled World is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. See our Terms of Service for more information.

Reporting Errors: Disabled World is an independent website, your assistance in reporting outdated or inaccurate information is appreciated. If you find an error please let us know.