Soft Drink Could Enhance Effects of an Anti-cancer Drug

Published: 2010/10/14
Author: American Chemical Society
Peer-Reviewed: N/A
Related Papers: Latest - Complete List

Synopsis: Experiments suggest a popular lemon-lime soft drink could play unexpected role in improving effectiveness of an oral anticancer drug. Experiments with an artificial stomach suggest that a popular lemon-lime soft drink could play an unexpected role in improving the effectiveness of an oral anticancer drug.

Main Digest

Experiments with an artificial stomach suggest that a popular lemon-lime soft drink could play an unexpected role in improving the effectiveness of an oral anticancer drug.

The experiments produced evidence that patients will absorb more of the unnamed drug, tested in Phase I in clinical trials, when taken with "flat" or degassed Sprite. The study appears in ACS' Molecular Pharmaceutics , a bi-monthly journal.

Faraj Atassi and colleagues note that efforts are underway to develop more anticancer medications that patients can take by mouth. However, biological variations among patients "due to variations in stomach acidity and other factors "can reduce the effectiveness of oral anticancer drugs. Such was the case with the unnamed anticancer drug in the study, identified only as "Compound X." There were wide differences in how the drug was absorbed in the first patients who took it.

The scientists combined Compound X with Captisol, a substance that helps improve the solubility of drug ingredients, and turned to the artificial stomach. That glass-and-plastic device is used to study how drugs and foods dissolve through the GI tract. They showed that Sprite seemed to control stomach acidity in a way likely to allow greater absorption of the drug into the body. Based on the results, the scientists suggest that patients in future clinical trials take the drug with Sprite.

Share This Information To:
𝕏.com Facebook Reddit

Discover Related Topics:

Information, Citing and Disclaimer

Disabled World is an independent disability community founded in 2004 to provide disability news and information to people with disabilities, seniors, their family and/or carers. See our homepage for informative reviews, exclusive stories and how-tos. You can connect with us on social media such as X.com and our Facebook page.

Permalink: <a href="https://www.disabled-world.com/health/cancer/treatment/sprite.php">Soft Drink Could Enhance Effects of an Anti-cancer Drug</a>

Cite This Page (APA): American Chemical Society. (2010, October 14). Soft Drink Could Enhance Effects of an Anti-cancer Drug. Disabled World. Retrieved October 4, 2023 from www.disabled-world.com/health/cancer/treatment/sprite.php

Disabled World provides general information only. The materials presented are never meant to substitute for qualified professional medical care, nor should they be construed as such. Funding is derived from advertisements or referral programs. Any 3rd party offering or advertising does not constitute an endorsement.