Skip to main content

Brain Tissue Regenerated in Traumatic Brain Injuries

  • Synopsis: Published: 2009-09-03 - An injectable biomaterial gel may help brain tissue grow at the site of a traumatic brain injury. For further information pertaining to this article contact: Clemson University.
  • Jump to:

Main Document

Biomaterial gel made up of both synthetic and natural sources has the potential to spur the growth of a patient's own neural stem cells in the body, structurally repairing the brain injury site.

Clemson University researcher regenerates brain tissue in traumatic injuries

An injectable biomaterial gel may help brain tissue grow at the site of a traumatic brain injury, according to findings by a Clemson University bioengineer.

Research by assistant professor of bioengineering Ning Zhang shows that the biomaterial gel made up of both synthetic and natural sources has the potential to spur the growth of a patient's own neural stem cells in the body, structurally repairing the brain injury site. In previous lab studies, Zhang has demonstrated the reconstruction of a complete vascular network at the injury site as an initial step toward brain tissue regeneration.

Zhang presented her findings Wednesday, Sept. 2, at the Military Research Forum in Kansas City. The conference is geared toward improving the overall health and welfare of the U.S. armed forces, their families, veterans and the American public.

"We have seen an increase in brain injuries due to combat, but our strategy can also potentially be applied to head injuries caused by car accidents, falls and gunshot wounds," said Zhang. "These results that we are seeing in adult lab rats are the first of its kind and show a sustained functional recovery in the animal model of TBI (traumatic brain injury). It also represents one of very few in the traumatic brain injury field that attempts structural repair of the lesion cavity using a tissue-engineering approach."

Zhang predicts the procedure may be ready for human testing in about three years.

The researcher says current approaches to traumatic brain injury have been focused on managing the primary injury using hypothermia or neuro-protection with pharmacological agents, all with limited success. With this new procedure, the hydrogel is injected into the lesion site to direct the response of neural stem cells in the brain to regenerate normal brain tissue at the lesion site.

The current research is supported by a $220,000 grant from the U.S. Department of Defense.





Information from our Traumatic Brain Injury: TBI & Concussion Information section - (Full List).


     What will I receive?

Loan Information for low income singles, families, seniors and disabled. Includes home, vehicle and personal loans.


Famous People with Disabilities - Well known people with disabilities and conditions who contributed to society.


List of awareness ribbon colors and their meaning. Also see our calendar of awareness dates.


Blood Pressure Chart - What should your blood pressure be. Also see information on blood group types and compatibility.


  1. Fear of Hostility Prevents Many Disabled People From Going Out
  2. Airport Security Experts, Disability Rights Advocates Call for Emergency Preparedness Training at Key Airports
  3. UCIC Launches Hardware Agnostic Alexa Voice Service Client
  4. How the NFL Came to Shape the Concussion Issue That Plagued It




Citation