Skip to main content
Accessibility  |  About  |  Contact  |  Privacy  |  Terms

Thyme Oil can Suppress Inflammation and Inhibit COX2

  • Published: 2010-01-13 : American Society for Biochemistry and Molecular Biology.
  • Synopsis: essential oils from thyme, clove, rose, eucalyptus, fennel and bergamot, can suppress the inflammatory COX-2 enzyme similar to resveratrol.

Main Document

For those who do not drink, researchers have found that six essential oils - from thyme, clove, rose, eucalyptus, fennel and bergamot, can suppress the inflammatory COX-2 enzyme, in a manner similar to resveratrol, the chemical linked with the health benefits of red wine. They also identified that the chemical carvacrol was primarily responsible for this suppressive activity.

These findings, appearing in the January issue of Journal of Lipid Research , provide more understanding of the health benefits of many botanical oils and provide a new avenue for anti-inflammatory drugs.

Essential oils from plants have long been a component of home remedies, and even today are used for their aromatherapy, analgesic (e.g. cough drops), or antibacterial properties. Of course, the exact way they work is not completely understood. However, Hiroyasu Inoue and colleagues in Japan believed that many essential oils might target COX-2 much like compounds in wine and tea.

So, they screened a wide range of commercially available oils and identified six (thyme, clove, rose, eucalyptus, fennel and bergamot) that reduced COX-2 expression in cells by at least 25%. Of these, thyme oil proved the most active, reducing COX-2 levels by almost 75%.

When Inoue and colleagues analyzed thyme oil, they found that the major component -carvacrol- was the primary active agent; in fact when they use pure carvacrol extracts in their tests COX-2 levels decreased by over 80%.

From the article: "Carvacrol, a component of thyme oil, activates PPAR-gamma and suppresses COX-2 expression" by Mariko Hotta, Rieko Nakata, Michiko Katsukawa, Kazuyuki Hori, Saori Takahashi, and Hiroyasu Inoue

Corresponding Author: Hiroyasu Inoue, Department of Food Science and Nutrition, Nara Women's University, Nara, Japan; Tel: +81-742-20-3458, Email: inoue@cc.nara-wu.ac.jp

The American Society for Biochemistry and Molecular Biology is a nonprofit scientific and educational organization with over 12,000 members in the United States and internationally. Most members teach and conduct research at colleges and universities. Others conduct research in various government laboratories, nonprofit research institutions and industry. The Society's student members attend undergraduate or graduate institutions.

Founded in 1906, the Society is based in Bethesda, Maryland, on the campus of the Federation of American Societies for Experimental Biology. The Society's purpose is to advance the science of biochemistry and molecular biology through publication of the Journal of Biological Chemistry, the Journal of Lipid Research , and Molecular and Cellular Proteomics, organization of scientific meetings, advocacy for funding of basic research and education, support of science education at all levels, and promoting the diversity of individuals entering the scientific work force.

Similar Topics

1 : Ginger Facts and Health Benefits : Disabled World.
2 : What is Ginseng? : Disabled World.
3 : Garlic Facts, Remedies, and Health Benefits : Disabled World.
4 : Indian Herbal Medicine: Cures for Constipation : Dr Deepak Acharya.
5 : Improving Health with Herbs and Spices : Stefanie Woodhouse.
From our Herbalism & Herbal Medicine section - Full List (35 Items)

Submit disability news, coming events, as well as assistive technology product news and reviews.


Loan Information for low income singles, families, seniors and disabled. Includes home, vehicle and personal loans.


Famous People with Disabilities - Well known people with disabilities and conditions who contributed to society.


List of awareness ribbon colors and their meaning. Also see our calendar of awareness dates.


Blood Pressure Chart - What should your blood pressure be, and information on blood group types/compatibility.





1 : Protein Levels in Spinal Fluid Correlate to Posture and Gait Difficulty in Parkinson's Disease
2 : Palliative Care Findings on Caregiver Depression, LGBT Partners, Moral Distress
3 : Circulation Journal's Go Red for Women Issue Focuses on Female Heart Health
4 : Wearable Stretchable Electronics Aid Stroke Recovery Treatment

Citation


Disclaimer: This site does not employ and is not overseen by medical professionals. Content on Disabled World is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. See our Terms of Service for more information.

Reporting Errors: Disabled World is an independent website, your assistance in reporting outdated or inaccurate information is appreciated. If you find an error please let us know.