Pain Relief for Knee Osteoarthritis with Traumeel and Zeel Intra-articular Injections

Introduction

A study of 232 patients was presented at the American College of Rheumatology 2014 Annual Meeting demonstrating that co-administered Traumeel (Tr14) and Zeel (Ze14) intra-articular (IA) injections are safe and effective treatments for moderate to severe pain associated with knee osteoarthritis (OA) versus IA placebo.

Main Digest

The data was discussed today in a podium presentation by Carlos J. Lozada, M.D., Professor of Clinical Medicine, University of Miami Miller School of Medicine.

In the multi-center, double-blind, randomized, controlled trial, patients with moderate-to-severe chronic knee OA were randomized to three weekly IA injections of either Tr14 and Ze14 or saline.

The primary efficacy variable was change in knee pain from baseline to end-of-study (week 17) as measured by the WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index) OA pain sub-scale.

Secondary measures included TOTAL WOMAC and sub-scores for stiffness and physical function, change in pain following a 50-foot walk, as well as patient and physician global assessments.

By day 15, patients experienced significant reductions in pain, and secondary endpoints were directionally consistent.

Of note, the study does not report any related serious adverse events. Adverse events were generally mild and reported as unrelated to treatment.

"In this study of 232 patients, Traumeel and Zeel provided statistically significant and clinically relevant pain relief for patients with osteoarthritis of the knee, a condition for which pain relief can be challenging to achieve," said Dr. Lozada. "I look forward to further research on this treatment to confirm and build on the findings in the study. This potentially represents an additional option in the management of osteoarthritis, especially for those patients who cannot tolerate non-steroidal anti-inflammatory drugs (NSAIDs), are not candidates for corticosteroid treatment or do not respond to other therapies."

Traumeel and Zeel injection solutions have been available globally for more than 60 years to help manage the pain of osteoarthritis. In the last 10 years, more than 1.5 million ampules of Traumeel and Zeel have been sold in the U.S.

"This study supports the clinical feedback we hear from healthcare professionals regarding positive outcomes with Traumeel and Zeel injections in knee osteoarthritis," said Jaclyn Chasse, ND, medical director, Emerson Ecologics. "We are proud to distribute prescription products like Traumeel and Zeel that are safe, effective and backed by clinical evidence."

Emerson Ecologics is the leading provider of injectable Traumeel and Zeel to qualified healthcare practitioners throughout the United States.

Attribution/Source(s):

This quality-reviewed publication was selected for publishing by the editors of Disabled World due to its significant relevance to the disability community. Originally authored by Emerson Ecologics LLC, and published on 2014/11/19 (Edit Update: 2020/11/22), the content may have been edited for style, clarity, or brevity. For further details or clarifications, Emerson Ecologics LLC can be contacted at emersonecologics.com. NOTE: Disabled World does not provide any warranties or endorsements related to this article.

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Cite This Page (APA): Emerson Ecologics LLC. (2014, November 19 - Last revised: 2020, November 22). Pain Relief for Knee Osteoarthritis with Traumeel and Zeel Intra-articular Injections. Disabled World. Retrieved September 9, 2024 from www.disabled-world.com/medical/clinical-trials/traumeel-zeel.php

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