Building Blocks for RNA Based Life Abundant in Our Galaxy
Topic: Anthropology and Disability
Author: Frontiers
Published: 2022/07/08 - Updated: 2024/03/05
Publication Type: Anthropology News - Peer-Reviewed: Yes
Contents: Summary - Definition - Introduction - Main - Related
Synopsis: Essential precursors for life on Earth were found to be abundant in interstellar Molecular Clouds and may have reached Earth inside meteors and comets. According to the 'RNA World' theory, nitriles and other building blocks for life needn't necessarily all have arisen on Earth itself: they might also have originated in space and 'hitchhiked' to the young Earth inside meteorites and comets during the 'Late Heavy Bombardment period, between 4.1 and 3.8 billion years ago. According to this scenario, life on Earth was initially based on RNA only, and DNA and protein enzymes evolved later. RNA can fulfill both functions: storing and copying information like DNA and catalyzing reactions like enzymes.
Introduction
Nitriles, a class of organic molecules with a cyano group, that is, a carbon atom bound with an unsaturated triple bond to a nitrogen atom, are typically toxic. But paradoxically, they are also a key precursor for molecules essential for life, such as ribonucleotides, composed of the nucleobases or 'letters' A, U, C, and G joined to a ribose and phosphate group, which together make up RNA. Now, a team of researchers from Spain, Japan, Chile, Italy, and the US shows that a wide range of nitriles occurs in interstellar space within the molecular cloud G+0.693-0.027, near the center of the Milky Way.
Main Digest
Dr. Víctor M. Rivilla, a researcher at the Center for Astrobiology of the Spanish National Research Council (CSIC) and the National Institute of Aerospace Technology (INTA) in Madrid, Spain, and the first author of the new study, said:
"Here we show that the chemistry that takes place in the interstellar medium can efficiently form multiple nitriles, which are key molecular precursors of the 'RNA World' scenario."
Possible 'RNA-only' world
According to this scenario, life on Earth was originally based on RNA only, and DNA and protein enzymes evolved later. RNA can fulfill both their functions: storing and copying information like DNA and catalyzing reactions like enzymes.
According to the RNA World theory, nitriles and other building blocks for life needn't necessarily all have arisen on Earth itself: they might also have originated in space and 'hitchhiked' to the young Earth inside meteorites and comets during the 'Late Heavy Bombardment period, between 4.1 and 3.8 billion years ago. In support, nitriles and other precursor molecules for nucleotides, lipids, and amino acids have been found inside contemporary comets and meteors.
But where in space could these molecules have come from?
Prime candidates are molecular clouds, dense and cold regions of the interstellar medium, and are suitable for forming complex molecules. For example, the molecular cloud G+0.693-0.027 has a temperature of around 100 K and is approximately three light-years across, with a mass approximately one thousand times that of our Sun. There's no evidence that stars are currently forming inside G+0.693-0.027, although scientists suspect that it might evolve to become a stellar nursery in the future.
"The chemical content of G+0.693-0.027 is similar to those of other star-forming regions in our galaxy and also to that of solar system objects like comets. This means that its study can give us important insights about the chemical ingredients that were available in the nebula that give rise to our planetary system," explained Rivilla.
Electromagnetic Spectra Studied
Rivilla and colleagues used two telescopes in Spain to study the electromagnetic spectra emitted by G+0.693-0.027: the 30-meter-wide IRAM telescope in Granada and the 40-meter-wide Yebes telescope in Guadalajara. They detected the nitriles cyanoallene (CH2CCHCN), propargyl cyanide (HCCCH2CN), and cyanopropyne, which hadn't yet been found in G+0.693-0.027, although they had been reported in 2019 in the TMC-1 dark cloud in the constellations Taurus and Auriga, a molecular cloud with very different conditions than G+0.693-0.027.
Rivilla et al. also found possible evidence for the occurrence in G+0.693-0.027 of cyanoformaldehyde (HCOCN) and glycolonitrile (HOCH2CN). Cyanoformaldehyde was detected for the first time in the molecular clouds TMC-1 and Sgr B2 in the constellation Sagittarius, and glycolonitrile in the Sun-like protostar IRAS16293-2422 B in the constellation Ophiuchus.
Other recent studies have also reported other RNA precursors inside G+0.693-0.027 such as glycolaldehyde (HCOCH2OH), urea (NH2CONH2), hydroxylamine (NH2OH), and 1,2-ethanediol (C2H4O2), confirming that the interstellar chemistry can provide the most basic ingredients for the 'RNA World.'
Nitriles Among Most Abundant Chemical Families in Space
Final author, Dr. Miguel A Requena-Torres, a lecturer at Towson University in Maryland, US, concluded:
"Thanks to our observations over the past few years, including the present results, we now know that nitriles are among the most abundant chemical families in the universe. We have found them in molecular clouds in the center of our galaxy, protostars of different masses, meteorites, and comets, and also in the atmosphere of Titan, Saturn's largest moon."
Second author Dr. Izaskun Jiménez-Serra, likewise a researcher at CSIC and INTA, looked ahead:
"We have detected so far several simple precursors of ribonucleotides, the building blocks of RNA. But there are still key missing molecules that are hard to detect. For example, we know that the origin of life on Earth probably also required other molecules, such as lipids, responsible for forming the first cells. Therefore we should also focus on understanding how lipids could be formed from simpler precursors available in the interstellar medium."
Attribution/Source(s):
This peer reviewed publication was selected for publishing by the editors of Disabled World due to its significant relevance to the disability community. Originally authored by Frontiers, and published on 2022/07/08 (Edit Update: 2024/03/05), the content may have been edited for style, clarity, or brevity. For further details or clarifications, Frontiers can be contacted at frontiersin.org. NOTE: Disabled World does not provide any warranties or endorsements related to this article.
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Cite This Page (APA): Frontiers. (2022, July 8 - Last revised: 2024, March 5). Building Blocks for RNA Based Life Abundant in Our Galaxy. Disabled World. Retrieved September 9, 2024 from www.disabled-world.com/disability/education/anthropology/rna-life.php
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